Martin James Stoddart
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Explore the profile of Martin James Stoddart including associated specialties, affiliations and a list of published articles.
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9
Citations
104
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Recent Articles
1.
Basic Principles of RNA Interference: Nucleic Acid Types and In Vitro Intracellular Delivery Methods
Isenmann M, Stoddart M, Schmelzeisen R, Gross C, Della Bella E, Rothweiler R
Micromachines (Basel)
. 2023 Jul;
14(7).
PMID: 37512632
Since its discovery in 1989, RNA interference (RNAi) has become a widely used tool for the in vitro downregulation of specific gene expression in molecular biological research. This basically involves...
2.
Breulmann F, Hatt L, Schmitz B, Wehrle E, Richards R, Della Bella E, et al.
Clin Transl Med
. 2023 Jan;
13(1):e1161.
PMID: 36629031
Background: Approximately 10% of all bone fractures result in delayed fracture healing or non-union; thus, the identification of biomarkers and prognostic factors is of great clinical interest. MicroRNAs (miRNAs) are...
3.
van der Heide D, Cidonio G, Stoddart M, DEste M
Biofabrication
. 2022 Aug;
14(4).
PMID: 36007496
In most cases, bone injuries heal without complications, however, there is an increasing number of instances where bone healing needs major clinical intervention. Available treatment options have severe drawbacks, such...
4.
Hasler J, Hatt L, Stoddart M, Armiento A
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33276559
Reverse transcription quantitative polymerase chain reaction (RT-qPCR) enables the monitoring of changes in cell phenotype via the high-throughput screening of numerous genes. RT-qPCR is a fundamental approach in numerous research...
5.
Rothweiler R, Basoli V, Duttenhoefer F, Kubosch D, Schmelzeisen R, Johnstone B, et al.
Front Bioeng Biotechnol
. 2020 Jul;
8:618.
PMID: 32676497
The use of human mesenchymal stromal cells (hMSCs) for cartilage regeneration has been hampered by the inherent donor variation of primary monolayer expanded cells. Although CD markers are typically used...
6.
Monaco G, El Haj A, Alini M, Stoddart M
Front Bioeng Biotechnol
. 2020 Apr;
8:243.
PMID: 32296689
Surgical strategies to treat articular cartilage injury such as microfracture, expose human bone marrow stem cells (hMSCs) to synovial fluid and its components. High molecular weight hyaluronan (hMwt HA) is...
7.
Behrendt P, Ladner Y, Stoddart M, Lippross S, Alini M, Eglin D, et al.
Am J Sports Med
. 2019 Dec;
48(1):210-221.
PMID: 31877102
Background: The treatment of osteochondral defects (OCDs) constitutes a major problem for orthopaedic surgeons. The altered mechanics and the cell types, with associated soluble factors derived from the exposed subchondral...
8.
Hatt L, Thompson K, Muller W, Stoddart M, Armiento A
Int J Mol Sci
. 2019 Nov;
20(22).
PMID: 31752206
The ability of bone-marrow-derived mesenchymal stem/stromal cells (BM-MSCs) to differentiate into osteoblasts makes them the ideal candidate for cell-based therapies targeting bone-diseases. Polyphosphate (polyP) is increasingly being studied as a...
9.
Stoddart M, Ettinger L, Hauselmann H
Biotechnol Bioeng
. 2006 Jun;
95(6):1043-51.
PMID: 16804949
Production of a de novo cartilage-like tissue construct is a goal for the repair of traumatic chondral defects. We aimed to enhance the matrix synthesis within a scaffold free, de...