Martin Graef
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Explore the profile of Martin Graef including associated specialties, affiliations and a list of published articles.
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28
Citations
5076
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Recent Articles
1.
2.
Dabrowski R, Tulli S, Graef M
J Cell Biol
. 2023 Apr;
222(7).
PMID: 37115156
During autophagy, rapid membrane assembly expands small phagophores into large double-membrane autophagosomes. Theoretical modeling predicts that the majority of autophagosomal phospholipids are derived from highly efficient non-vesicular phospholipid transfer (PLT)...
3.
Grossbach J, Gillet L, Clement-Ziza M, Schmalohr C, Schubert O, Schutter M, et al.
Mol Syst Biol
. 2022 May;
18(5):e10712.
PMID: 35574625
Genomic variation impacts on cellular networks by affecting the abundance (e.g., protein levels) and the functional states (e.g., protein phosphorylation) of their components. Previous work has focused on the former,...
4.
Kochan D, Mawer J, Massen J, Tishinov K, Parekh S, Graef M, et al.
J Cell Sci
. 2021 Aug;
134(15).
PMID: 34350963
Gene expression involves regulation of chromatin structure and transcription, as well as processing of the transcribed mRNA. While there are feedback mechanisms, it is not clear whether these include crosstalk...
5.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
6.
Sawa-Makarska J, Baumann V, Coudevylle N, von Bulow S, Nogellova V, Abert C, et al.
Science
. 2020 Sep;
369(6508).
PMID: 32883836
Autophagosomes form de novo in a manner that is incompletely understood. Particularly enigmatic are autophagy-related protein 9 (Atg9)-containing vesicles that are required for autophagy machinery assembly but do not supply...
7.
Gross A, Graef M
J Cell Biol
. 2020 Jun;
219(7).
PMID: 32584933
Lee et al. (2020. Nat. Cell Biol.https://doi.org/10.1038/s41556-019-0459-2) and, in this issue, Tomioka et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201910063) describe the targeted degradation of nuclear pore complexes (NPCs) by selective autophagy,...
8.
Graef M
F1000Res
. 2020 Apr;
9.
PMID: 32266060
Autophagy is a conserved catabolic process critical for cell homeostasis with broad implications for aging and age-associated diseases. A defining feature of autophagy is the formation of a specialized transient...
9.
Cui R, Medeiros T, Willemsen D, Iasi L, Collier G, Graef M, et al.
Cell
. 2020 Mar;
180(6):1272-1279.
PMID: 32200802
No abstract available.
10.
Schutter M, Graef M
Autophagy
. 2020 Feb;
16(4):770-771.
PMID: 32013690
During (macro)autophagy, cells form transient organelles, termed autophagosomes, to target a broad spectrum of substrates for degradation critical to cellular and organismal health. Driven by rapid membrane assembly, an initially...