Martin Closter Jespersen
Overview
Explore the profile of Martin Closter Jespersen including associated specialties, affiliations and a list of published articles.
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9
Citations
1298
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Recent Articles
1.
Jensen K, Rantos V, Jappe E, Olsen T, Jespersen M, Jurtz V, et al.
Sci Rep
. 2019 Oct;
9(1):14530.
PMID: 31601838
The interaction between the class I major histocompatibility complex (MHC), the peptide presented by the MHC and the T-cell receptor (TCR) is a key determinant of the cellular immune response....
2.
Mahajan S, Yan Z, Jespersen M, Jensen K, Marcatili P, Nielsen M, et al.
BMC Bioinformatics
. 2019 Oct;
20(1):490.
PMID: 31601176
Background: The development of accurate epitope prediction tools is important in facilitating disease diagnostics, treatment and vaccine development. The advent of new approaches making use of antibody and TCR sequence...
3.
Dhanda S, Mahajan S, Paul S, Yan Z, Kim H, Jespersen M, et al.
Nucleic Acids Res
. 2019 May;
47(W1):W502-W506.
PMID: 31114900
The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools.iedb.org/) is a companion website to the IEDB that provides computational tools focused on the prediction and analysis of B and T cell...
4.
Jespersen M, Mahajan S, Peters B, Nielsen M, Marcatili P
Front Immunol
. 2019 Mar;
10:298.
PMID: 30863406
B-cells can neutralize pathogenic molecules by targeting them with extreme specificity using receptors secreted or expressed on their surface (antibodies). This is achieved via molecular interactions between the paratope (i.e.,...
5.
Schantz Klausen M, Jespersen M, Nielsen H, Jensen K, Jurtz V, Sonderby C, et al.
Proteins
. 2019 Feb;
87(6):520-527.
PMID: 30785653
The ability to predict local structural features of a protein from the primary sequence is of paramount importance for unraveling its function in absence of experimental structural information. Two main...
6.
Mahajan S, Vita R, Shackelford D, Lane J, Schulten V, Zarebski L, et al.
Front Immunol
. 2018 Dec;
9:2688.
PMID: 30515166
The Immune Epitope Database (IEDB) is a free public resource which catalogs experiments characterizing immune epitopes. To accommodate data from next generation repertoire sequencing experiments, we recently updated how we...
7.
Jespersen M, Peters B, Nielsen M, Marcatili P
Nucleic Acids Res
. 2017 May;
45(W1):W24-W29.
PMID: 28472356
Antibodies have become an indispensable tool for many biotechnological and clinical applications. They bind their molecular target (antigen) by recognizing a portion of its structure (epitope) in a highly specific...
8.
Ison J, Rapacki K, Menager H, Kalas M, Rydza E, Chmura P, et al.
Nucleic Acids Res
. 2015 Nov;
44(D1):D38-47.
PMID: 26538599
Life sciences are yielding huge data sets that underpin scientific discoveries fundamental to improvement in human health, agriculture and the environment. In support of these discoveries, a plethora of databases...
9.
Schantz Klausen M, Anderson M, Jespersen M, Nielsen M, Marcatili P
Nucleic Acids Res
. 2015 May;
43(W1):W349-55.
PMID: 26007650
The accurate structural modeling of B- and T-cell receptors is fundamental to gain a detailed insight in the mechanisms underlying immunity and in developing new drugs and therapies. The LYRA...