Martin Bartl
Overview
Explore the profile of Martin Bartl including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
125
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Recent Articles
1.
Ewald J, Bartl M, Kaleta C
Biochem Soc Trans
. 2017 Jul;
45(4):1035-1043.
PMID: 28754658
Understanding optimality principles shaping the evolution of regulatory networks controlling metabolism is crucial for deriving a holistic picture of how metabolism is integrated into key cellular processes such as growth,...
2.
Ewald J, Bartl M, Dandekar T, Kaleta C
PLoS Comput Biol
. 2017 Feb;
13(2):e1005371.
PMID: 28212377
A precise and rapid adjustment of fluxes through metabolic pathways is crucial for organisms to prevail in changing environmental conditions. Based on this reasoning, many guiding principles that govern the...
3.
Bartl M, Pfaff M, Ghallab A, Driesch D, Henkel S, Hengstler J, et al.
Arch Toxicol
. 2015 Oct;
89(11):2069-78.
PMID: 26438405
The rodent liver eliminates toxic ammonia. In mammals, three enzymes (or enzyme systems) are involved in this process: glutaminase, glutamine synthetase and the urea cycle enzymes, represented by carbamoyl phosphate...
4.
de Hijas-Liste G, Balsa-Canto E, Ewald J, Bartl M, Li P, Banga J, et al.
BMC Bioinformatics
. 2015 May;
16:163.
PMID: 25982966
Background: Adjusting the capacity of metabolic pathways in response to rapidly changing environmental conditions is an important component of microbial adaptation strategies to stochastic environments. In this work, we use...
5.
Ewald J, Kotzing M, Bartl M, Kaleta C
Metabolites
. 2015 May;
5(2):252-69.
PMID: 25927816
In this work, we investigate optimality principles behind synthesis strategies for protein complexes using a dynamic optimization approach. We show that the cellular capacity of protein synthesis has a strong...
6.
Bartl M, Kotzing M, Schuster S, Li P, Kaleta C
Nat Commun
. 2013 Aug;
4:2243.
PMID: 23979724
To survive in fluctuating environmental conditions, microorganisms must be able to quickly react to environmental challenges by upregulating the expression of genes encoding metabolic pathways. Here we show that protein...
7.
Wessely F, Bartl M, Guthke R, Li P, Schuster S, Kaleta C
Mol Syst Biol
. 2011 Jul;
7:515.
PMID: 21772263
While previous studies have shed light on the link between the structure of metabolism and its transcriptional regulation, the extent to which transcriptional regulation controls metabolism has not yet been...
8.
Bartl M, Li P, Schuster S
Biosystems
. 2010 Apr;
101(1):67-77.
PMID: 20420882
The time course of enzyme concentrations in metabolic pathways can be predicted on the basis of the optimality criterion of minimizing the time period in which an essential product is...