Martin B Madsen
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Explore the profile of Martin B Madsen including associated specialties, affiliations and a list of published articles.
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13
Citations
350
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Recent Articles
1.
Rath E, Palma Medina L, Jahagirdar S, Mosevoll K, Damas J, Madsen M, et al.
Clin Immunol
. 2023 Mar;
249:109276.
PMID: 36871764
Objective: Early stages with streptococcal necrotizing soft tissue infections (NSTIs) are often difficult to discern from cellulitis. Increased insight into inflammatory responses in streptococcal disease may guide correct interventions and...
2.
Palma Medina L, Rath E, Jahagirdar S, Bruun T, Madsen M, Stralin K, et al.
J Clin Invest
. 2021 Jul;
131(14).
PMID: 34263738
BACKGROUNDNecrotizing soft-tissue infections (NSTIs) are rapidly progressing infections frequently complicated by septic shock and associated with high mortality. Early diagnosis is critical for patient outcome, but challenging due to vague...
3.
Hedetoft M, Madsen M, Perner A, Garred P, Hyldegaard O
Acta Anaesthesiol Scand
. 2021 Jun;
65(9):1293-1299.
PMID: 34138468
Background: A marked inflammatory response in necrotising soft-tissue infection (NSTI) may contribute to the severe clinical course. Intravenous polyspecific immunoglobulin G (IVIG) is used by some as adjuvant treatment for...
4.
Kjaer M, Meyhoff T, Madsen M, Hjortrup P, Moller M, Egerod I, et al.
Acta Anaesthesiol Scand
. 2019 Dec;
64(3):410-416.
PMID: 31828753
Background: In patients with septic shock, mortality is high, and survivors experience long-term physical, mental and social impairments. The ongoing Conservative vs Liberal Approach to fluid therapy of Septic Shock...
5.
Polzik P, Grondal O, Tavenier J, Madsen M, Andersen O, Hedetoft M, et al.
Sci Rep
. 2019 Mar;
9(1):5098.
PMID: 30911053
Necrotizing soft tissue infections (NSTI) have a 90-day mortality rate of 18-22%. Tools are needed for estimating the prognosis and severity of NSTI upon admission. We evaluated soluble urokinase-type plasminogen...
6.
Krag M, Marker S, Perner A, Wetterslev J, Wise M, Schefold J, et al.
N Engl J Med
. 2018 Oct;
379(23):2199-2208.
PMID: 30354950
Background: Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear. Methods: In this European, multicenter, parallel-group,...
7.
Rygard S, Jonsson A, Madsen M, Perner A, Holst L, Johansson P, et al.
Intensive Care Med
. 2018 Jan;
44(2):204-217.
PMID: 29372291
Purpose: Patients in the intensive care unit (ICU) are often transfused with red blood cells (RBC). During storage, the RBCs and storage medium undergo changes, which may have clinical consequences....
8.
Hansen M, Rasmussen L, Garred P, Pilely K, Wahl A, Perner A, et al.
Shock
. 2017 Sep;
49(6):667-674.
PMID: 28863028
Background: The nitric oxide system could play an important role in the pathophysiology related to necrotizing soft tissue infection (NSTI). Accordingly, we investigated the association between plasma nitrite level at...
9.
Madsen M, Hjortrup P, Hansen M, Lange T, Norrby-Teglund A, Hyldegaard O, et al.
Intensive Care Med
. 2017 Apr;
43(11):1585-1593.
PMID: 28421246
Purpose: The aim of the INSTINCT trial was to assess the effect of intravenous polyspecific immunoglobulin G (IVIG) compared with placebo on self-reported physical function in intensive care unit (ICU)...
10.
Siemens N, Chakrakodi B, Mairpady Shambat S, Morgan M, Bergsten H, Hyldegaard O, et al.
JCI Insight
. 2016 Oct;
1(10):e87882.
PMID: 27699220
Necrotizing fasciitis caused by group A streptococcus (GAS) is a life-threatening, rapidly progressing infection. At present, biofilm is not recognized as a potential problem in GAS necrotizing soft tissue infections...