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Martha F Kramer

Explore the profile of Martha F Kramer including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Kramer M, Jurak I, Pesola J, Boissel S, Knipe D, Coen D
Virology . 2011 Jul; 417(2):239-47. PMID: 21782205
Several herpes simplex virus 1 microRNAs are encoded within or near the latency associated transcript (LAT) locus, and are expressed abundantly during latency. Some of these microRNAs can repress the...
2.
Kramer M
Curr Protoc Mol Biol . 2011 Jul; Chapter 15:Unit 15.10. PMID: 21732315
This unit presents a specific and sensitive quantitative reverse-transcription PCR (RT-qPCR) method for measuring individual microRNAs (miRNAs) in tissue or cultured cells. miRNAs are 17 to 24 nucleotides (nt) in...
3.
Jurak I, Kramer M, Mellor J, van Lint A, Roth F, Knipe D, et al.
J Virol . 2010 Feb; 84(9):4659-72. PMID: 20181707
Certain viruses use microRNAs (miRNAs) to regulate the expression of their own genes, host genes, or both. Previous studies have identified a limited number of miRNAs expressed by herpes simplex...
4.
Kramer M, Coen D
Curr Protoc Cytom . 2008 Sep; Appendix 3:Appendix 3K. PMID: 18770830
This unit describes a method for amplifying DNA enzymatically by the polymerase chain reaction (PCR), including procedures to quickly determine conditions for successful amplification of the sequence and primer sets...
5.
Umbach J, Kramer M, Jurak I, Karnowski H, Coen D, Cullen B
Nature . 2008 Jul; 454(7205):780-3. PMID: 18596690
Herpesviruses are characterized by their ability to maintain life-long latent infections in their animal hosts. However, the mechanisms that allow establishment and maintenance of the latent state remain poorly understood....
6.
Kramer M, Coen D
Curr Protoc Immunol . 2008 Apr; Chapter 10:10.20.1-10.20.10. PMID: 18432685
This unit describes a method for amplifying DNA enzymatically by the polymerase chain reaction (PCR) and for optimizing this reaction for the sequence and primer set of interest. Important variables...
7.
Kramer M, Coen D
Curr Protoc Protein Sci . 2008 Apr; Appendix 4:A.4J.1-A.4J.8. PMID: 18429219
This appendix describes the methodology behind PCR and gives a method for amplifying DNA enzymatically by the PCR and for optimizing this reaction for the sequence and primer set of...
8.
L Bookout A, Cummins C, Mangelsdorf D, Pesola J, Kramer M
Curr Protoc Mol Biol . 2008 Feb; Chapter 15:Unit 15.8. PMID: 18265376
Extensive detail on the application of the real-time quantitative polymerase chain reaction (QPCR) for the analysis of gene expression is provided in this unit. The protocols are designed for high-throughput,...
9.
Cui C, Griffiths A, Li G, Silva L, Kramer M, Gaasterland T, et al.
J Virol . 2006 May; 80(11):5499-508. PMID: 16699030
MicroRNAs (miRNAs) are key regulators of gene expression in higher eukaryotes. Recently, miRNAs have been identified from viruses with double-stranded DNA genomes. To attempt to identify miRNAs encoded by herpes...
10.
Cook W, Kramer M, Walker R, Burwell T, Holman H, Coen D, et al.
Virol J . 2004 Oct; 1:5. PMID: 15507126
Inflammatory cytokines and infiltrating T cells are readily detected in herpes simplex virus (HSV) infected mouse cornea and trigeminal ganglia (TG) during the acute phase of infection, and certain cytokines...