Marta Martinez-Vicente
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Explore the profile of Marta Martinez-Vicente including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Montpeyo M, Perez-Carmona N, Cubero E, Delgado A, Ruano A, Carrillo J, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39795868
Mutations in the gene, which encodes the lysosomal enzyme glucocerebrosidase (GCase), are associated with Gaucher disease and increased risk of Parkinson's disease. This study describes the discovery and characterization of...
2.
Martinez-Vicente M, Vila M
Cold Spring Harb Perspect Med
. 2024 Dec;
PMID: 39694692
Autophagy is a vital cellular process responsible for the degradation of proteins, organelles, and other cellular components within lysosomes. In neurons, basal autophagy is indispensable for maintaining cellular homeostasis and...
3.
Gordaliza-Alaguero I, Sanchez-Fernandez-de-Landa P, Radivojevikj D, Villarreal L, Arauz-Garofalo G, Gay M, et al.
Autophagy
. 2024 Dec;
:1-22.
PMID: 39675054
MFN1 (mitofusin 1) and MFN2 are key players in mitochondrial fusion, endoplasmic reticulum (ER)-mitochondria juxtaposition, and macroautophagy/autophagy. However, the mechanisms by which these proteins participate in these processes are poorly...
4.
Lerche S, Wurster I, Valente E, Avenali M, Samaniego D, Martinez-Vicente M, et al.
NPJ Parkinsons Dis
. 2024 Oct;
10(1):198.
PMID: 39448669
Variants in GBA1 result in dysregulated sphingolipids. We investigated five CSF d18:1 sphingolipid species in a longitudinal multicenter cohort comprising people with Parkinson's Disease and Dementia with Lewy bodies with...
5.
Castillo-Ribelles L, Arranz-Amo J, Hernandez-Vara J, Samaniego-Toro D, Enriquez-Calzada S, Pozo S, et al.
Anal Chem
. 2024 Jul;
96(31):12875-12882.
PMID: 39047057
Mutations in GBA1, encoding glucocerebrosidase beta 1 (GCase), are the most common genetic risk factor for Parkinson's disease (PD). GCase dysfunction leads to an accumulation of glucosylceramide (GluCer) substrates in...
6.
Malhotra S, Fissolo N, Rodriguez-Rivera C, Monreal E, Montpeyo M, Urcelay E, et al.
Clin Transl Med
. 2024 Apr;
14(4):e1654.
PMID: 38591764
No abstract available.
7.
Valdor R, Martinez-Vicente M
Biomedicines
. 2024 Feb;
12(2).
PMID: 38397859
Chaperone-mediated autophagy (CMA) is a selective proteolytic pathway in the lysosomes. Proteins are recognized one by one through the detection of a KFERQ motif or, at least, a KFERQ-like motif,...
8.
Magana J, Deus C, Baldellou L, Avellanet M, Gea-Rodriguez E, Enriquez-Calzada S, et al.
PLoS One
. 2023 Nov;
18(11):e0293774.
PMID: 37992028
Parkinson's disease (PD) is characterized by the progressive dopaminergic neuron degeneration, resulting in striatal dopamine deficiency. Mitochondrial dysfunction and oxidative stress are associated with PD pathogenesis. Physical activity (PA) has...
9.
Pradas E, Martinez-Vicente M
Cells
. 2023 Jan;
12(1).
PMID: 36611984
gene variants were the first genetic risk factor for Parkinson's disease. encodes the lysosomal enzyme glucocerebrosidase (GBA), which is involved in sphingolipid metabolism. GBA exhibits a complex physiological function that...
10.
Navarro-Romero A, Fernandez-Gonzalez I, Riera J, Montpeyo M, Albert-Bayo M, Lopez-Royo T, et al.
NPJ Parkinsons Dis
. 2022 Oct;
8(1):126.
PMID: 36202848
Mutations in the GBA gene that encodes the lysosomal enzyme β-glucocerebrosidase (GCase) are a major genetic risk factor for Parkinson's disease (PD). In this study, we generated a set of...