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Marta Maglione

Explore the profile of Marta Maglione including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 737
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Recent Articles
1.
Karpova A, Hiesinger P, Kuijpers M, Albrecht A, Kirstein J, Andres-Alonso M, et al.
Neuron . 2025 Feb; PMID: 40010347
Neurons are long-lived postmitotic cells that capitalize on autophagy to remove toxic or defective proteins and organelles to maintain neurotransmission and the integrity of their functional proteome. Mutations in autophagy...
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Guitton-Spassky T, Junge F, Singh A, Schade B, Achazi K, Maglione M, et al.
Nanoscale . 2023 Apr; 15(17):7781-7791. PMID: 37016756
Enzymes are more selective and efficient than synthetic catalysts but are limited by difficult recycling. This is overcome by immobilisation, namely through encapsulation, with the main drawback of this method...
3.
Ghelani T, Escher M, Thomas U, Esch K, Lutzkendorf J, Depner H, et al.
Sci Adv . 2023 Feb; 9(7):eade7804. PMID: 36800417
At presynaptic active zones (AZs), conserved scaffold protein architectures control synaptic vesicle (SV) release by defining the nanoscale distribution and density of voltage-gated Ca channels (VGCCs). While AZs can potentiate...
4.
Tadic J, Ring J, Jerkovic A, Ristic S, Maglione M, Dengjel J, et al.
Cell Stress . 2022 Nov; 6(5):61-64. PMID: 36448030
Alzheimer's disease (AD) is the most common form of dementia with millions of people affected worldwide. Pathophysiological manifestations of AD include the extracellular accumulation of amyloid beta (Abeta) pep-tides, products...
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Ring J, Tadic J, Ristic S, Poglitsch M, Bergmann M, Radic N, et al.
EMBO Mol Med . 2022 Apr; 14(5):e13952. PMID: 35373908
Amyloid beta 42 (Abeta42) is the principal trigger of neurodegeneration during Alzheimer's disease (AD). However, the etiology of its noxious cellular effects remains elusive. In a combinatory genetic and proteomic...
7.
Orlando M, Dvorzhak A, Bruentgens F, Maglione M, Rost B, Sigrist S, et al.
PLoS Biol . 2021 Jun; 19(6):e3001149. PMID: 34153028
Synaptic plasticity is a cellular model for learning and memory. However, the expression mechanisms underlying presynaptic forms of plasticity are not well understood. Here, we investigate functional and structural correlates...
8.
Liang Y, Piao C, Beuschel C, Toppe D, Kollipara L, Bogdanow B, et al.
Cell Rep . 2021 Apr; 35(2):108941. PMID: 33852845
Mitochondrial function declines during brain aging and is suspected to play a key role in age-induced cognitive decline and neurodegeneration. Supplementing levels of spermidine, a body-endogenous metabolite, has been shown...
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Pooryasin A, Maglione M, Schubert M, Matkovic-Rachid T, Hasheminasab S, Pech U, et al.
Nat Commun . 2021 Mar; 12(1):1932. PMID: 33771998
The physical distance between presynaptic Ca channels and the Ca sensors triggering the release of neurotransmitter-containing vesicles regulates short-term plasticity (STP). While STP is highly diversified across synapse types, the...
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Fukaya R, Maglione M, Sigrist S, Sakaba T
Proc Natl Acad Sci U S A . 2021 Feb; 118(9). PMID: 33622791
The cyclic adenosine monophosphate (cAMP)-dependent potentiation of neurotransmitter release is important for higher brain functions such as learning and memory. To reveal the underlying mechanisms, we applied paired pre- and...