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Marta Epeldegui

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Articles 37
Citations 437
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Recent Articles
1.
Wiley K, Martinez L, Kwon D, Knorr D, Epeldegui M, Fox M
Am J Reprod Immunol . 2025 Jan; 93(2):e70027. PMID: 39854121
Problem: Regulatory B-cells (Bregs, CD19CD24CD38) are a specialized B-cell subset that suppresses immune responses and potentially contribute to the maintenance of an immune-privileged environment for fetal development during pregnancy. However,...
2.
Martinez L, Comin-Anduix B, Guemes-Aragon M, Ibarrondo J, Detels R, Mimiaga M, et al.
Front Immunol . 2024 Sep; 15():1441994. PMID: 39324141
People living with HIV (PLWH) are at higher risk of developing lymphoma. In this study, we performed cytometry by time-of-flight (CyTOF) on peripheral blood mononuclear cells of cART-naïve HIV+ individuals...
3.
Cauble E, Reynolds P, Epeldegui M, Andra S, Magpantay L, Narasimhan S, et al.
Cytokine . 2024 Sep; 184:156753. PMID: 39299102
Introduction: Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants that have been linked to a number of health outcomes, including those related to immune dysfunction. However, there are limited...
4.
Martinez L, Magpantay L, Guo Y, Hegde P, Detels R, Hussain S, et al.
Front Immunol . 2023 Oct; 14:1259007. PMID: 37809067
Introduction: Extracellular vesicles are membrane-bound structures secreted into the extracellular milieu by cells and can carry bioactive molecules. There is emerging evidence suggesting that EVs play a role in the...
5.
Epeldegui M, Chang D, Lee J, Magpantay L, Borok M, Bukuru A, et al.
J Acquir Immune Defic Syndr . 2023 Jun; 94(2):165-173. PMID: 37368929
Background: Guidelines for limited-stage human immunodeficiency virus-associated Kaposi sarcoma (AIDS/KS) recommend antiretroviral therapy (ART) as initial treatment. However, many such individuals show worsening KS and require additional chemotherapy. Methods to...
6.
Shi M, Zong X, Hur J, Birmann B, Martinez-Maza O, Epeldegui M, et al.
EBioMedicine . 2023 Apr; 91:104566. PMID: 37075493
Background: Gut microbial dysbiosis contributes to colorectal cancer (CRC) pathogenesis, possibly mediated in part by increased intestinal permeability to endotoxin lipopolysaccharide (LPS), microbial translocation, and subsequent endotoxemia and inflammation. However,...
7.
Lam A, Roshan R, Miley W, Labo N, Zhen J, Kurland A, et al.
J Virol . 2023 Feb; 97(2):e0160022. PMID: 36757205
Infection by Kaposi sarcoma-associated herpesvirus (KSHV) can cause severe consequences, such as cancers and lymphoproliferative diseases. Whole inactivated viruses (WIV) with chemically destroyed genetic materials have been used as antigens...
8.
Salvatore B, Resop R, Gordon B, Epeldegui M, Martinez-Maza O, Comin-Anduix B, et al.
Cells . 2023 Jan; 12(2). PMID: 36672230
Humoral immune response is important in fighting pathogens by the production of specific antibodies by B cells. In germinal centers, T follicular helper (TFH) cells provide important help to B-cell...
9.
Martinez L, Ibarrondo J, Guo Y, Penichet M, Epeldegui M
J Immunol . 2022 Nov; 210(1):33-39. PMID: 36445393
Follicular CD8+CXCR5+ T cells are a specialized CD8+ T cell subset with unique follicular-homing capabilities that have been reported to display effector functions in viral immunity, tumor immunity, and autoimmunity....
10.
Martinez L, Lensing S, Chang D, Magpantay L, Mitsuyasu R, Ambinder R, et al.
Sci Rep . 2022 Jun; 12(1):9185. PMID: 35655072
Emerging evidence shows that tumor cells secrete extracellular vesicles (EVs) that carry bioactive cell surface markers, such as programmed death-ligand 1 (PD-L1), which can modulate immune responses and inhibit anti-tumor...