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Marta E Alberto

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Articles 34
Citations 292
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Recent Articles
1.
Abad-Montero D, Gandioso A, Izquierdo-Garcia E, Chumillas S, Rovira A, Bosch M, et al.
J Am Chem Soc . 2025 Feb; 147(9):7360-7376. PMID: 39953993
Hypoxia, a hallmark of many solid tumors, is linked to increased cancer aggressiveness, metastasis, and resistance to conventional therapies, leading to poor patient outcomes. This challenges the efficiency of photodynamic...
2.
Cole H, Vali A, Roque 3rd J, Shi G, Talgatov A, Kaur G, et al.
Inorg Chem . 2024 May; 63(21):9735-9752. PMID: 38728376
A series of Ru(II) complexes incorporating two 4,4'-bis(trifluoromethyl)-2,2'-bipyridine (4,4'-btfmb) coligands and thienyl-appended imidazo[4,5-][1,10]phenanthroline (IP-T) ligands was characterized and assessed for phototherapy effects toward cancer cells. The [Ru(4,4'-btfmb)(IP-T)] scaffold has greater...
3.
Cole H, Vali A, Roque 3rd J, Shi G, Kaur G, Hodges R, et al.
Inorg Chem . 2023 Dec; 62(51):21181-21200. PMID: 38079387
Ru(II) polypyridyl complexes have gained widespread attention as photosensitizers for photodynamic therapy (PDT). Herein, we systematically investigate a series of the type [Ru(phen)(IP-T)], featuring 1,10-phenanthroline (phen) coligands and imidazo[4,5-][1,10]phenanthroline ligands...
4.
Fraix A, Parisi C, Longobardi G, Conte C, Pastore A, Stornaiuolo M, et al.
Biomacromolecules . 2023 Jul; 24(8):3887-3897. PMID: 37467426
The role of nitric oxide (NO) as an "unconventional" therapeutic and the strict dependence of biological effects on its concentration require the generation of NO with precise spatiotemporal control. The...
5.
Alberto M, Frances-Monerris A
Phys Chem Chem Phys . 2022 Aug; 24(32):19584-19594. PMID: 35943094
The photoreactivity of relatively large transition metal complexes is often limited to the description of the static potential energy surfaces of the involved electronic states. While useful to grasp some...
6.
Roque Iii J, Cole H, Barrett P, Lifshits L, Hodges R, Kim S, et al.
J Am Chem Soc . 2022 Apr; 144(18):8317-8336. PMID: 35482975
Ru(II) complexes that undergo photosubstitution reactions from triplet metal-centered (MC) excited states are of interest in photochemotherapy (PCT) due to their potential to produce cytotoxic effects in hypoxia. Dual-action systems...
7.
Majeed S, Amin M, Attaby F, Alberto M, Soliman A
Molecules . 2022 Feb; 27(3). PMID: 35164228
Three new palladium complexes ([Pd(DABA)Cl], [Pd(CPDA)Cl], and [Pd(HZPY)Cl]) bearing dinitrogen ligands (DABA: 3,4-diaminobenzoic acid; CPDA: 4-chloro-o-phenylenediamine; HZPY: 2-hydraziniopyridine) were synthesized, characterized, and tested against breast cancer (MCF-7), prostate carcinoma cell...
8.
Roque 3rd J, Barrett P, Cole H, Lifshits L, Shi G, Monro S, et al.
Chem Sci . 2021 Mar; 11(36):9784-9806. PMID: 33738085
Hypoxia presents a two-fold challenge in the treatment of cancer, as low oxygen conditions induce biological changes that make malignant tissues simultaneously more aggressive and less susceptible to standard chemotherapy....
9.
Roque 3rd J, Barrett P, Cole H, Lifshits L, Bradner E, Shi G, et al.
Inorg Chem . 2020 Oct; 59(22):16341-16360. PMID: 33126792
Hypoxia presents a challenge to anticancer therapy, reducing the efficacy of many available treatments. Photodynamic therapy is particularly susceptible to hypoxia, given that its mechanism relies on oxygen. Herein, we...
10.
Ponte F, Alberto M, De Simone B, Russo N, Sicilia E
Inorg Chem . 2019 Jul; 58(15):9882-9889. PMID: 31343162
Two-component Pt-BODIPY dyes were recently proposed as potential multitarget agents able to conjugate the photobased photodynamic therapy (PDT) treatment with the classical chemotherapy approach based on Pt complexes. A careful...