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Marloes Broekmans

Explore the profile of Marloes Broekmans including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 621
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Recent Articles
1.
Verkleij C, Frerichs K, Broekmans M, Absalah S, Maas-Bosman P, Kruyswijk S, et al.
Oncotarget . 2020 Nov; 11(45):4076-4081. PMID: 33227097
B-cell maturation antigen (BCMA)-targeting bispecific antibodies and bispecific T-cell engagers (BiTEs) redirect T-cells to BCMA-expressing multiple myeloma (MM) cells. These MM cells are subsequently eliminated via various mechanisms of action...
2.
van Groningen T, Akogul N, Westerhout E, Chan A, Hasselt N, Zwijnenburg D, et al.
Nat Commun . 2019 Apr; 10(1):1530. PMID: 30948783
Transition between differentiation states in development occurs swift but the mechanisms leading to epigenetic and transcriptional reprogramming are poorly understood. The pediatric cancer neuroblastoma includes adrenergic (ADRN) and mesenchymal (MES)...
3.
Frerichs K, Nagy N, Lindenbergh P, Bosman P, Marin Soto J, Broekmans M, et al.
Expert Rev Clin Immunol . 2018 Feb; 14(3):197-206. PMID: 29465271
Multiple myeloma (MM) is generally an incurable hematological malignancy with heterogeneous overall survival rates ranging from a few months to more than 10 years. Survival is especially poor for patients...
4.
van Groningen T, Koster J, Valentijn L, Zwijnenburg D, Akogul N, Hasselt N, et al.
Nat Genet . 2017 Jun; 49(8):1261-1266. PMID: 28650485
Neuroblastoma and other pediatric tumors show a paucity of gene mutations, which has sparked an interest in their epigenetic regulation. Several tumor types include phenotypically divergent cells, resembling cells from...
5.
Molenaar J, Domingo-Fernandez R, Ebus M, Lindner S, Koster J, Drabek K, et al.
Nat Genet . 2012 Oct; 44(11):1199-206. PMID: 23042116
LIN28B regulates developmental processes by modulating microRNAs (miRNAs) of the let-7 family. A role for LIN28B in cancer has been proposed but has not been established in vivo. Here, we...