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Marlie M Maestas

Explore the profile of Marlie M Maestas including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 52
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Recent Articles
1.
Kelley A, Shunkarova M, Maestas M, Gale S, Hogrebe N, Millman J
bioRxiv . 2024 Nov; PMID: 39605713
Stem cell-derived islets (SC-islets) consists of multiple hormone-producing cell types and offer a promising therapeutic avenue for treating type 1 diabetes (T1D). Currently, the composition of cell types generated within...
2.
Maestas M, Bui M, Millman J
Stem Cells Transl Med . 2024 Aug; 13(10):949-958. PMID: 39159002
Stem cell-derived islets (SC-islets) offer the potential to be an unlimited source of cells for disease modeling and the treatment of diabetes. SC-islets can be genetically modified, treated with chemical...
3.
Maestas M, Ishahak M, Augsornworawat P, Veronese-Paniagua D, Maxwell K, Velazco-Cruz L, et al.
Nat Commun . 2024 Jul; 15(1):5567. PMID: 38956087
Diabetes involves the death or dysfunction of pancreatic β-cells. Analysis of bulk sequencing from human samples and studies using in vitro and in vivo models suggest that endoplasmic reticulum and...
4.
Augsornworawat P, Hogrebe N, Ishahak M, Schmidt M, Marquez E, Maestas M, et al.
Nat Cell Biol . 2023 Aug; 25(10):1546. PMID: 37558893
No abstract available.
5.
Augsornworawat P, Hogrebe N, Ishahak M, Schmidt M, Marquez E, Maestas M, et al.
Nat Cell Biol . 2023 May; 25(6):904-916. PMID: 37188763
Insulin-producing β cells created from human pluripotent stem cells have potential as a therapy for insulin-dependent diabetes, but human pluripotent stem cell-derived islets (SC-islets) still differ from their in vivo...
6.
Ashley R, Runyan C, Maestas M, Trigo E, Silver G
Front Vet Sci . 2021 Sep; 8:650687. PMID: 34485423
The placenta, a unique organ that only develops during pregnancy, is essential for nutrient, oxygen, and waste exchange between offspring and mother. Yet, despite its importance, the placenta remains one...
7.
McIntosh S, Maestas M, Dobson J, Quinn K, Runyan C, Ashley R
Biol Reprod . 2020 Nov; 104(2):468-478. PMID: 33141178
Early pregnancy features complex signaling between fetal trophoblast cells and maternal endometrium directing major peri-implantation events including localized inflammation and remodeling to establish proper placental development. Proinflammatory mediators are important...
8.
McIntosh S, Maxam C, Maestas M, Quinn K, Ashley R
Am J Reprod Immunol . 2019 Aug; 82(5):e13181. PMID: 31420980
Problem: Chemokines help coordinate inflammation within the fetal-maternal microenvironment during gestation. The chemokine CXCL12 signaling through its receptor CXCR4 regulates inflammatory activity, but this phenomenon is not well understood during...
9.
Runyan C, McIntosh S, Maestas M, Quinn K, Boren B, Ashley R
Biol Reprod . 2019 Apr; 101(1):102-111. PMID: 31004477
Placenta development is characterized by extensive angiogenesis and vascularization but if these processes are compromised placental dysfunction occurs, which is the underlying cause of pregnancy complications such as preeclampsia and...