Alpha 2.0
Login Register
» Authors » Markus Thiemann

Markus Thiemann

Explore the profile of Markus Thiemann including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 262
Followers 0
Related Specialties
Oncology
Radiology
Biomedical Engineering
Top 10 Co-Authors
Peter E Huber
Andreas E Kulozik
Claudia Blattmann
Volker Ehemann
Jurgen Debus
Susanne Oertel
Albrecht Stenzinger
Wilko Weichert
Marc Bischof
Oliver J Schmitz
Published In
Radiat Oncol
J Chromatogr B Analyt Technol Biomed Life Sci
Int J Radiat Oncol Biol Phys
Phys Rev Lett
Carcinogenesis
Affiliations
Soon will be listed here.
Recent Articles
1.
Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient-derived osteosarcoma cells and synergizes with cisplatin and talazoparib
Heidler C, Roth E, Thiemann M, Blattmann C, Perez R, Huber P, et al.
Int J Cancer . 2019 Nov; 147(4):1059-1070. PMID: 31782150
Progress in the systemic control of osteosarcoma has been limited over the past decades thus indicating the urgent clinical need for the development of novel treatment strategies. Therefore, we have...
2.
Single-Gap Superconductivity and Dome of Superfluid Density in Nb-Doped SrTiO_{3}
Thiemann M, Beutel M, Dressel M, Lee-Hone N, Broun D, Fillis-Tsirakis E, et al.
Phys Rev Lett . 2018 Jun; 120(23):237002. PMID: 29932713
SrTiO_{3} exhibits a superconducting dome upon doping with Nb, with a maximum critical temperature T_{c}≈0.4  K. Using microwave stripline resonators at frequencies from 2 to 23 GHz and temperatures down...
3.
Histone deacetylase inhibition sensitizes osteosarcoma to heavy ion radiotherapy
Blattmann C, Oertel S, Thiemann M, Dittmar A, Roth E, Kulozik A, et al.
Radiat Oncol . 2015 Jul; 10:146. PMID: 26178881
Background: Minimal improvements in treatment or survival of patients with osteosarcoma have been achieved during the last three decades. Especially in the case of incomplete tumor resection, prognosis remains poor....
4.
Establishment of a patient-derived orthotopic osteosarcoma mouse model
Blattmann C, Thiemann M, Stenzinger A, Roth E, Dittmar A, Witt H, et al.
J Transl Med . 2015 May; 13:136. PMID: 25926029
Background: Osteosarcoma (OS) is the most common pediatric primary malignant bone tumor. As the prognosis for patients following standard treatment did not improve for almost three decades, functional preclinical models...
5.
In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model
Thiemann M, Oertel S, Ehemann V, Weichert W, Stenzinger A, Bischof M, et al.
Radiat Oncol . 2012 Mar; 7:52. PMID: 22458853
Purpose: Histone deacetylase inhibitors are promising new substances in cancer therapy and have also been shown to sensitize different tumor cells to irradiation (XRT). We explored the effect as well...
6.
Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines
Oertel S, Thiemann M, Richter K, Weber K, Huber P, Lopez Perez R, et al.
Radiat Oncol . 2011 Sep; 6:119. PMID: 21933400
Introduction: The pan-HDAC inhibitor (HDACI) suberoylanilide hydroxamic acid (SAHA) has previously shown to be a radio-sensitizer to conventional photon radiotherapy (XRT) in pediatric sarcoma cell lines. Here, we investigate its...
7.
Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition
Blattmann C, Oertel S, Ehemann V, Thiemann M, Huber P, Bischof M, et al.
Int J Radiat Oncol Biol Phys . 2010 Jul; 78(1):237-45. PMID: 20646843
Purpose: Histone deacetylase inhibitors (HDACIs) can enhance the sensitivity of cells to photon radiation treatment (XRT) by altering numerous molecular pathways. We investigated the effect of pan-HDACIs such as suberoylanilide...
8.
Production of different phenotypes from the same genotype in the same environment by developmental variation
Vogt G, Huber M, Thiemann M, van den Boogaart G, Schmitz O, Schubart C
J Exp Biol . 2008 Feb; 211(Pt 4):510-23. PMID: 18245627
The phenotype of an organism is determined by the genes, the environment and stochastic developmental events. Although recognized as a basic biological principle influencing life history, susceptibility to diseases, and...
9.
Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice
Arlt V, Stiborova M, Henderson C, Thiemann M, Frei E, Aimova D, et al.
Carcinogenesis . 2008 Jan; 29(3):656-65. PMID: 18204078
Many studies using mammalian cellular and subcellular systems have demonstrated that polycyclic aromatic hydrocarbons, including benzo[a]pyrene (BaP), are metabolically activated by cytochrome P450s (CYPs). In order to evaluate the role...
10.
Determination of the DNA methylation level of the marbled crayfish: an increase in sample throughput by an optimised sample preparation
Schiewek R, Wirtz M, Thiemann M, Plitt K, Vogt G, Schmitz O
J Chromatogr B Analyt Technol Biomed Life Sci . 2006 Dec; 850(1-2):548-52. PMID: 17175207
Using a previously described capillary electrophoretic method with laser-induced fluorescence detection the genomic methylation level can be determined exactly. We present a sample preparation that eliminates the surplus of fluorescence...