Markku Miettinen
Overview
Explore the profile of Markku Miettinen including associated specialties, affiliations and a list of published articles.
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Articles
238
Citations
10759
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Recent Articles
1.
Lasota J, Kaczorowski M, Chlopek M, Milek-Krupa J, Szczepaniak M, Ylaya K, et al.
Hum Pathol
. 2025 Jan;
155:105717.
PMID: 39824298
Colorectal carcinoma brain metastases (n = 60) were studied using next-generation sequencing and immunohistochemistry. RAS and BRAF mutations were detected in 58.2% and 7.3% of cases, respectively. Patients with RAS-...
2.
Rosenblum J, Cole Y, Dang D, Lookian P, Alkaissi H, Patel M, et al.
JNCI Cancer Spectr
. 2025 Jan;
9(1).
PMID: 39821441
Background: Head and neck paragangliomas (HNPGLs) are typically slow-growing, hormonally inactive tumors of parasympathetic paraganglia. Inactivation of prolyl-hydroxylase domain-containing 2 protein causing indirect gain-of-function of hypoxia-inducible factor-2α (HIF-2α), encoded by...
3.
Gallanis A, Bowden C, Lopez R, Gamble L, Samaranayake S, Payne C, et al.
J Gastrointest Surg
. 2024 Nov;
29(1):101889.
PMID: 39547590
Background: Prophylactic total gastrectomy (PTG) is performed in carriers of CDH1 pathogenic and likely pathogenic (P/LP) variants and is becoming more frequent with broader use of germline genetic testing. There...
4.
Lucas C, Gross A, Romo C, Dehner C, Lazar A, Miettinen M, et al.
Neuro Oncol
. 2024 Nov;
27(3):616-624.
PMID: 39500722
Consensus recommendations published in 2017 histologically defining atypical neurofibromatous neoplasm of uncertain biologic potential (ANNUBP) and malignant peripheral nerve sheath tumor (MPNST) were codified in the 2021 WHO Classification of...
5.
Kaczorowski M, Ylaya K, Chlopek M, Lasota J, Miettinen M
Am J Surg Pathol
. 2024 Sep;
49(1):62-72.
PMID: 39319626
Epithelial chemosensory cells in hollow organs, also known as tuft cells, were implicated in tumorigenesis, including a tuft cell-like small cell lung carcinoma. Expression of the POU2F3 transcription factor is...
6.
Kaczorowski M, Ylaya K, Chlopek M, Taniyama D, Pommier Y, Lasota J, et al.
Am J Surg Pathol
. 2024 Aug;
PMID: 39185596
Schlafen 11 (SLFN11), a DNA/RNA helicase, acts as a regulator of cellular response to replicative stress and irreversibly triggers replication block and cell death. Several preclinical in vitro studies and...
7.
Kaczorowski M, Lasota J, Halon A, Miettinen M
Arch Pathol Lab Med
. 2024 Aug;
148(11):1179-1180.
PMID: 39175461
No abstract available.
8.
Kato S, Koshino A, Lasota J, Komura M, Wang C, Ebi M, et al.
Appl Immunohistochem Mol Morphol
. 2024 Jul;
32(8):362-370.
PMID: 39076030
SATB2 has been reported to be highly specific for lower gastrointestinal tract tumors. On the basis of its ileum-colon conversion effects, which involve the activation of colonic genes in cooperation...
9.
Lasota J, Thompson L, Chlopek M, Kowalik A, Miettinen M
Appl Immunohistochem Mol Morphol
. 2024 Jul;
32(7):322-325.
PMID: 38975712
Background: We report a nasal cavity unusual perivascular epithelioid cell tumor (PEComa) mimicking mucosal melanoma. Methods: Immunohistochemistry was performed using BenchMark Ultra and panel of antibodies. The Ion Torrent platform...
10.
Desai P, Takahashi N, Kumar R, Nichols S, Malin J, Hunt A, et al.
Cell Rep Med
. 2024 Jun;
5(6):101610.
PMID: 38897168
Small-cell lung cancer (SCLC) is the most fatal form of lung cancer. Intratumoral heterogeneity, marked by neuroendocrine (NE) and non-neuroendocrine (non-NE) cell states, defines SCLC, but the cell-extrinsic drivers of...