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Mark W Lingen

Explore the profile of Mark W Lingen including associated specialties, affiliations and a list of published articles. Areas
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Articles 133
Citations 3387
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Recent Articles
1.
Rosenberg A, Juloori A, Jelinek M, Agrawal N, Cursio J, Cipriani N, et al.
JAMA Oncol . 2025 Mar; PMID: 40048190
Importance: Neoadjuvant immunotherapy in human papillomavirus (HPV)-negative locoregionally advanced (LA) head and neck squamous cell carcinoma (HNSCC) appears promising, yet its role in nonsurgical treatment for head and neck cancer...
2.
Hieromnimon H, Trzcinska A, Wen F, Howard F, Dolezal J, Dyer E, et al.
Oral Oncol . 2025 Mar; 163:107207. PMID: 40043423
Objectives: Human papillomavirus (HPV) influences the pathobiology of Head and Neck Squamous Cell Carcinomas (HSNCCs). While deep learning shows promise in detecting HPV from hematoxylin and eosin (H&E) stained slides,...
3.
Wang C, Yu K, Chen T, Tsai M, Kang C, Chien C, et al.
Oral Oncol . 2025 Feb; 162:107210. PMID: 39947008
Background: To characterize multistate oral carcinogenesis, we conducted a cohort study of patients with oral precancer and a parallel case-control study of oral cancers and controls in Taiwan. Methods: During...
4.
Mishra V, Singh A, Korzinkin M, Cheng X, Wing C, Sarkisova V, et al.
J Exp Clin Cancer Res . 2025 Jan; 44(1):11. PMID: 39794830
Background: Adenoid cystic carcinoma (ACC) is a rare glandular malignancy, commonly originating in salivary glands of the head and neck. Given its protracted growth, ACC is usually diagnosed in advanced...
5.
Khattri A, Sheikh N, Agrawal N, Kaushik S, Kochanny S, Ginat D, et al.
Cancer Gene Ther . 2024 Jul; 31(10):1477-1485. PMID: 39085630
Cetuximab induces responses in about 13% of head and neck squamous cell carcinomas (HNSCC). We describe the molecular mechanism of acquired resistance to cetuximab, which could be overcome by switching...
6.
Rosenberg A, Agrawal N, Juloori A, Cursio J, Gooi Z, Blair E, et al.
JAMA Oncol . 2024 Jun; 10(7):923-931. PMID: 38842838
Importance: Immune checkpoint inhibitors improve survival in recurrent and/or metastatic head and neck cancer, yet their role in curative human papillomavirus-positive oropharyngeal cancer (HPV+ OPC) remains undefined. Neoadjuvant nivolumab and...
7.
Tota J, Engels E, Lingen M, Agrawal N, Kerr A, Zumsteg Z, et al.
J Clin Oncol . 2023 Nov; 42(15):1745-1753. PMID: 38033283
Purpose: The incidence of oral tongue cancers has increased since the 1980s among US men and women for unknown reasons. We investigated associations of inflammatory tongue conditions with risk of...
8.
Nigam N, Bernard B, Sevilla S, Kim S, Dar M, Tsai D, et al.
Cell Rep . 2023 Jul; 42(7):112823. PMID: 37463106
Cancers often display immune escape, but the mechanisms are incompletely understood. Herein, we identify SMYD3 as a mediator of immune escape in human papilloma virus (HPV)-negative head and neck squamous...
9.
Wolk R, Lingen M
Head Neck Pathol . 2023 May; 17(2):292-298. PMID: 37184731
Head and neck squamous cell carcinoma (HNSCC) is the world's 6th most common malignancy. Oral cavity SCC (OCSCC) represents approximately one third of the HNSCC cases diagnosed annually in the...
10.
Goldberg M, Manzi A, Birdi A, Laporte B, Conway P, Cantin S, et al.
Nat Commun . 2022 Dec; 13(1):7865. PMID: 36543765
No abstract available.