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Mark W Cunningham Jr

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Citations 800
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Recent Articles
1.
Jones K, Smith S, Smith J, Castillo A, Burkes A, Howard A, et al.
J Appl Physiol (1985) . 2025 Jan; 138(3):666-680. PMID: 39884662
Women living in an impoverished environment after birth have an increased risk of developing postpartum depression (PP-Dep) and hypertension (PP-HTN). The mechanisms underlying these heightened risks are unknown and understudied....
2.
Meadors A, Comley K, Cottrell J, Ibhahim T, Cunningham Jr M, Amaral L
Am J Reprod Immunol . 2024 Jan; 91(1):e13805. PMID: 38282604
Preeclampsia (PE) is a multisystem disorder characterized by new onset hypertension in mid-late gestation and can include multi-organ dysfunction with or without proteinuria. It affects 5%-7% of all pregnancies in...
3.
Booz G, Kennedy D, Bowling M, Robinson T, Azubuike D, Fisher B, et al.
Biol Sex Differ . 2021 Nov; 12(1):58. PMID: 34727994
Women with preeclampsia (PE) have a greater risk of developing hypertension, cardiovascular disease (CVD), and renal disease later in life. Angiotensin II type I receptor agonistic autoantibodies (AT1-AAs) are elevated...
4.
Cottrell J, Witcher A, Comley K, Cunningham Jr M, Ibrahim T, Cornelius D, et al.
Am J Physiol Regul Integr Comp Physiol . 2021 Feb; 320(5):R719-R727. PMID: 33533305
Preeclampsia (PE) is characterized by new-onset hypertension in association with elevated natural killer (NK) cells and inflammatory cytokines, which are likely culprits for decreased fetal weight during PE pregnancies. As...
5.
Cunningham Jr M, Amaral L, Campbell N, Cornelius D, Ibrahim T, Vaka V, et al.
Biol Sex Differ . 2021 Jan; 12(1):4. PMID: 33407826
Two important clinical features of preeclampsia (PE) are hypertension and fetal growth restriction. The reduced uterine perfusion pressure (RUPP) preclinical rat model of PE exhibits both of these features. Moreover,...
6.
Duncan J, Azubuike D, Booz G, Fisher B, Williams J, Fan F, et al.
Hypertens Pregnancy . 2020 Oct; 39(4):451-460. PMID: 33119997
Women with preeclampsia (PE) and reduced uterine perfusion pressure (RUPP) pre-clinical rat model of PE have elevated angiotensin II type 1 receptor agonistic autoantibodies (AT1-AA) and cerebrovascular dysfunction. Sprague Dawley...
7.
Amaral L, Cottrell J, Comley K, Cunningham Jr M, Witcher A, Vaka V, et al.
Pregnancy Hypertens . 2020 Sep; 22:151-155. PMID: 32980622
Preeclampsia (PE) is characterized by new onset hypertension in association with elevated soluble fms-like tyrosine kinase-1 (sFlt-1) and preproendothelin-1 (PPET-1) levels. Currently there is no effective treatment for PE except...
8.
Elfarra J, Cottrell J, Cornelius D, Cunningham Jr M, Faulkner J, Ibrahim T, et al.
Pregnancy Hypertens . 2019 Dec; 19:226-232. PMID: 31806502
Preeclampsia (PE) is new onset hypertension during pregnancy associated with increased uterine artery resistance (UARI) and an imbalance among CD4 + T lymphocytes and natural killer (NK) cells. We have...
9.
Cunningham Jr M, Vaka V, McMaster K, Ibrahim T, Cornelius D, Amaral L, et al.
Pregnancy Hypertens . 2019 Mar; 15:72-77. PMID: 30825931
Women with preeclampsia (PE) have increased mean arterial pressure (MAP), natural killer (NK) cells, reactive oxygen species (ROS), and agonistic autoantibodies to the angiotensin II type 1 receptor (AT1-AA). AT1-AA's...
10.
Harmon A, Ibrahim T, Cornelius D, Amaral L, Cunningham Jr M, Wallace K, et al.
Pregnancy Hypertens . 2019 Mar; 15:7-11. PMID: 30825930
Preeclampsia (PE), new onset hypertension during pregnancy, is associated with a proinflammatory profile compared to normal pregnancy (NP). We hypothesize that CD4 T cells from PE patient placentas cause PE...