Mark Selby
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Explore the profile of Mark Selby including associated specialties, affiliations and a list of published articles.
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21
Citations
3430
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Recent Articles
11.
Patel M, Kim J, Theodros D, Tam A, Velarde E, Kochel C, et al.
J Immunother Cancer
. 2016 May;
4:28.
PMID: 27190629
Background: Glioblastoma (GBM) is a poorly immunogenic neoplasm treated with focused radiation. Immunotherapy has demonstrated synergistic survival effects with stereotactic radiosurgery (SRS) in murine GBM. GITR is a co-stimulatory molecule...
12.
Dahan R, Sega E, Engelhardt J, Selby M, Korman A, Ravetch J
Cancer Cell
. 2015 Sep;
28(3):285-95.
PMID: 26373277
Immune checkpoint blockade of the programmed cell death protein 1 (PD-1) pathway by monoclonal antibodies (Abs) has shown promising clinical benefit in the treatment of multiple cancer types. We elucidated...
13.
Gardiner D, Lalezari J, Lawitz E, DiMicco M, Ghalib R, Reddy K, et al.
PLoS One
. 2013 May;
8(5):e63818.
PMID: 23717490
Unlabelled: Expression of the programmed death 1 (PD-1) receptor and its ligands are implicated in the T cell exhaustion phenotype which contributes to the persistence of several chronic viral infections,...
14.
Olds W, Sundarajoo S, Selby M, Cletus B, Fredericks P, Izake E
Appl Spectrosc
. 2012 Apr;
66(5):530-7.
PMID: 22524958
In this paper, spatially offset Raman spectroscopy (SORS) is demonstrated for noninvasively investigating the composition of drug mixtures inside an opaque plastic container. The mixtures consisted of three components including...
15.
Woo S, Turnis M, Goldberg M, Bankoti J, Selby M, Nirschl C, et al.
Cancer Res
. 2011 Dec;
72(4):917-27.
PMID: 22186141
Inhibitory receptors on immune cells are pivotal regulators of immune escape in cancer. Among these inhibitory receptors, CTLA-4 (targeted clinically by ipilimumab) serves as a dominant off-switch while other receptors...
16.
Bettini M, Szymczak-Workman A, Forbes K, Castellaw A, Selby M, Pan X, et al.
J Immunol
. 2011 Aug;
187(7):3493-8.
PMID: 21873518
Lymphocyte activation gene-3 (LAG-3; CD223) is a CD4 homolog that is required for maximal regulatory T cell function and for the control of CD4(+) and CD8(+) T cell homeostasis. Lag3(-)(/)(-)...
17.
Brahmer J, Drake C, Wollner I, Powderly J, Picus J, Sharfman W, et al.
J Clin Oncol
. 2010 Jun;
28(19):3167-75.
PMID: 20516446
Purpose: Programmed death-1 (PD-1), an inhibitory receptor expressed on activated T cells, may suppress antitumor immunity. This phase I study sought to determine the safety and tolerability of anti-PD-1 blockade...
18.
Lin Y, Kwon T, Polo J, Zhu Y, Coates S, Crawford K, et al.
J Virol
. 2008 May;
82(15):7492-503.
PMID: 18508900
Broad, multispecific CD4(+) and CD8(+) T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated...
19.
Vajdy M, Selby M, Medina-Selby A, Coit D, Hall J, Tandeske L, et al.
J Gen Virol
. 2006 Jul;
87(Pt 8):2253-2262.
PMID: 16847121
Although approximately 3 % of the world's population is infected with Hepatitis C virus (HCV), there is no prophylactic vaccine available. This study reports the design, cloning and purification of...
20.
OHagan D, Singh M, Dong C, Ugozzoli M, Berger K, Glazer E, et al.
Vaccine
. 2004 Nov;
23(5):672-80.
PMID: 15542189
We initially evaluated in mice the ability of naked DNA encoding intracellular forms of the E1E2 envelope proteins from HCV to induce antibody responses and compared the responses induced with...