Mark S Keller
Overview
Explore the profile of Mark S Keller including associated specialties, affiliations and a list of published articles.
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13
Citations
218
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Recent Articles
1.
Keller M, Gold I, McCallum C, Manz T, Kharchenko P, Gehlenborg N
Nat Methods
. 2024 Sep;
22(1):63-67.
PMID: 39333268
Multiomics technologies with single-cell and spatial resolution make it possible to measure thousands of features across millions of cells. However, visual analysis of high-dimensional transcriptomic, proteomic, genome-mapped and imaging data...
2.
Gisch D, Brennan M, Lake B, Basta J, Keller M, Ferreira R, et al.
Nat Commun
. 2024 Jan;
15(1):433.
PMID: 38199997
There is a need to define regions of gene activation or repression that control human kidney cells in states of health, injury, and repair to understand the molecular pathogenesis of...
3.
Moore J, Basurto-Lozada D, Besson S, Bogovic J, Bragantini J, Brown E, et al.
Histochem Cell Biol
. 2023 Jul;
160(3):223-251.
PMID: 37428210
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across...
4.
Sieberts S, Borzymowski H, Guan Y, Huang Y, Matzner A, Page A, et al.
PLOS Digit Health
. 2023 Mar;
2(3):e0000208.
PMID: 36976789
One of the promising opportunities of digital health is its potential to lead to more holistic understandings of diseases by interacting with the daily life of patients and through the...
5.
Moore J, Basurto-Lozada D, Besson S, Bogovic J, Bragantini J, Brown E, et al.
bioRxiv
. 2023 Mar;
PMID: 36865282
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across...
6.
LYi S, Keller M, Dandawate A, Taing L, Chen C, Brown M, et al.
Bioinformatics
. 2023 Jan;
39(2).
PMID: 36688700
Summary: The regulation of genes by cis-regulatory elements (CREs) is complex and differs between cell types. Visual analysis of large collections of chromatin profiles across diverse cell types, integrated with...
7.
Cheng F, Keller M, Qu H, Gehlenborg N, Wang Q
IEEE Trans Vis Comput Graph
. 2022 Sep;
29(1):591-601.
PMID: 36155452
Reference-based cell-type annotation can significantly reduce time and effort in single-cell analysis by transferring labels from a previously-annotated dataset to a new dataset. However, label transfer by end-to-end computational methods...
8.
Wang X, Zhang H, Xiong X, Hong C, Weber G, Brat G, et al.
J Biomed Inform
. 2022 Aug;
134:104176.
PMID: 36007785
Objective: For multi-center heterogeneous Real-World Data (RWD) with time-to-event outcomes and high-dimensional features, we propose the SurvMaximin algorithm to estimate Cox model feature coefficients for a target population by borrowing...
9.
Weber G, Hong C, Xia Z, Palmer N, Avillach P, LYi S, et al.
NPJ Digit Med
. 2022 Jun;
5(1):74.
PMID: 35697747
Given the growing number of prediction algorithms developed to predict COVID-19 mortality, we evaluated the transportability of a mortality prediction algorithm using a multi-national network of healthcare systems. We predicted...
10.
Manz T, Gold I, Patterson N, McCallum C, Keller M, Herr 2nd B, et al.
Nat Methods
. 2022 May;
19(5):515-516.
PMID: 35545714
No abstract available.