Mark R Wormald
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Explore the profile of Mark R Wormald including associated specialties, affiliations and a list of published articles.
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66
Citations
3293
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Recent Articles
1.
OBrien M, Murray G, Gogoi D, Yusuf A, McCarthy C, Wormald M, et al.
Int J Mol Sci
. 2022 Mar;
23(5).
PMID: 35269582
Alpha-1 antitrypsin (AAT) is the canonical serine protease inhibitor of neutrophil-derived proteases and can modulate innate immune mechanisms through its anti-inflammatory activities mediated by a broad spectrum of protein, cytokine,...
2.
Liu Z, Jenkinson S, Yoshihara A, Wormald M, Izumori K, Fleet G
Molecules
. 2019 Oct;
24(20).
PMID: 31635397
A practical synthesis of the very rare sugar d-idose and the stable building blocks for d-idose, d-iduronic, and d-idonic acids from -heptonic acid requires only isopropylidene protection, Shing silica gel-supported...
3.
Martinez R, Jenkinson S, Nakagawa S, Kato A, Wormald M, Fleet G, et al.
Amino Acids
. 2019 May;
51(7):991-998.
PMID: 31079215
DMDP acetic acid [N-carboxymethyl-2,5-dideoxy-2,5-imino-D-mannitol] 5 from Stevia rebaudiana is the first isolated natural amino acid derived from iminosugars bearing an N-alkyl acid side chain; it is clear from GCMS studies...
4.
Reeves E, Dunlea D, McQuillan K, ODwyer C, Carroll T, Saldova R, et al.
J Immunol
. 2019 Feb;
202(8):2240-2253.
PMID: 30796179
Alpha-1 antitrypsin (AAT) is an acute phase protein that possesses immune-regulatory and anti-inflammatory functions independent of antiprotease activity. AAT deficiency (AATD) is associated with early-onset emphysema and chronic obstructive pulmonary...
5.
Reeves E, ODwyer C, Dunlea D, Wormald M, Hawkins P, Alfares M, et al.
Am J Respir Crit Care Med
. 2018 Jul;
198(8):1099-1102.
PMID: 30011228
No abstract available.
6.
Yu C, Gao K, Zhu L, Wang W, Wang L, Zhang F, et al.
Sci Rep
. 2017 Jul;
7:46385.
PMID: 28753200
This corrects the article DOI: 10.1038/srep20029.
7.
Hayes J, Wormald M, Rudd P, Davey G
J Inflamm Res
. 2016 Nov;
9:209-219.
PMID: 27895507
Therapeutic antibodies hold great promise for the treatment of cancer and autoimmune diseases, and developments in antibody-drug conjugates and bispecific antibodies continue to enhance treatment options for patients. Immunoglobulin (Ig)...
8.
Liu Z, Yoshihara A, Jenkinson S, Wormald M, Estevez R, Fleet G, et al.
Org Lett
. 2016 Aug;
18(16):4112-5.
PMID: 27487167
Ease of separation of petrol-soluble acetonides derived from the triacetonide of methyl glucoheptonate allows scalable syntheses of rare sugars containing the l-gluco or d-gulo structural motif with any oxidation level...
9.
Gilgunn S, Millan Martin S, Wormald M, Zapatero-Rodriguez J, Conroy P, OKennedy R, et al.
PLoS One
. 2016 Jul;
11(7):e0159859.
PMID: 27459092
Recent exploitation of the avian immune system has highlighted its suitability for the generation of high-quality, high-affinity antibodies to a wide range of antigens for a number of therapeutic and...
10.
Liu Z, Yoshihara A, Kelly C, Heap J, Marqvorsen M, Jenkinson S, et al.
Chemistry
. 2016 Jul;
22(35):12557-65.
PMID: 27439720
In the search for alternative non-metabolizable inducers in the l-rhamnose promoter system, the synthesis of fifteen 6-deoxyhexoses from l-rhamnose demonstrates the value of synergy between biotechnology and chemistry. The readily...