Mark Li
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Explore the profile of Mark Li including associated specialties, affiliations and a list of published articles.
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35
Citations
1197
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Recent Articles
11.
Li M, Shao F, Qian Q, Yu W, Zhang Z, Chen B, et al.
Mol Ther Nucleic Acids
. 2021 Sep;
26:307-320.
PMID: 34513312
Micropeptides (microproteins) encoded by transcripts previously annotated as long noncoding RNAs (lncRNAs) are emerging as important mediators of fundamental biological processes in health and disease. Here, we applied two computational...
12.
Mondaca S, Lebow E, Namakydoust A, Razavi P, Reis-Filho J, Shen R, et al.
Lung Cancer
. 2021 Jul;
159:66-73.
PMID: 34311346
Objectives: Liquid biopsy for plasma circulating tumor DNA (ctDNA) next-generation sequencing (NGS) can detect ALK fusions, though data on clinical utility of this technology in the real world is limited....
13.
Awad M, Liu S, Rybkin I, Arbour K, Dilly J, Zhu V, et al.
N Engl J Med
. 2021 Jun;
384(25):2382-2393.
PMID: 34161704
Background: Clinical trials of the KRAS inhibitors adagrasib and sotorasib have shown promising activity in cancers harboring KRAS glycine-to-cysteine amino acid substitutions at codon 12 (KRAS). The mechanisms of acquired...
14.
Smith M, Thomas S, Gormley M, Chowdhury S, Olmos D, Oudard S, et al.
Clin Cancer Res
. 2021 Jun;
27(16):4539-4548.
PMID: 34112710
Purpose: In the placebo-controlled SPARTAN study, apalutamide added to androgen-deprivation therapy (ADT) improved metastasis-free survival, second progression-free survival (PFS2), and overall survival (OS) in patients with nonmetastatic castration-resistant prostate cancer...
15.
Nunes S, Feric N, Pahnke A, Miklas J, Li M, Coles J, et al.
ACS Biomater Sci Eng
. 2021 Jan;
3(9):1911-1921.
PMID: 33440549
Animal models have been instrumental in providing insight into the molecular basis of disease. While such information has been successfully applied to the study of human disease, this translation would...
16.
Li M, Yamada S, Shi A, Singh R, Rolland T, Jeon R, et al.
Stem Cells Transl Med
. 2020 Oct;
10(3):385-397.
PMID: 33098750
To optimize the regenerative proficiency of stem cells, a cardiopoietic protein-based cocktail consisting of multiple growth factors has been developed and advanced into clinical trials for treatment of ischemic heart...
17.
Bansal A, Pandey M, Yamada S, Goyal R, Schmit N, Jeon R, et al.
Nucl Med Biol
. 2020 Sep;
90-91:23-30.
PMID: 32957056
Introduction: Radiolabeling of stem cells with a positron emitting radioisotope represents a major advancement in regenerative biotherapy enabling non-invasive imaging. To assess the value of such an approach in a...
18.
Zhang Z, Qian Q, Li M, Shao F, Ding W, Lira V, et al.
Autophagy
. 2020 Jun;
17(8):1841-1855.
PMID: 32597296
Defective macroautophagy/autophagy and a failure to initiate the adaptive unfolded protein response (UPR) in response to the endoplasmic reticulum (ER) stress contributes to obesity-associated metabolic dysfunction. However, whether and how...
19.
Itchins M, Lau B, Hudson A, Westman H, Xia C, Hayes S, et al.
Oncologist
. 2020 Jun;
25(8):641-649.
PMID: 32558067
Since its discovery in 2007, we have seen the lives of patients diagnosed with advanced anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancers (NSCLC) transform with the advent of molecular...
20.
Yamoah E, Li M, Shah A, Elliott K, Cheah K, Xu P, et al.
Ageing Res Rev
. 2020 Mar;
59:101042.
PMID: 32173536
Age-related hearing loss (ARHL) is the most prevalent sensory deficit. ARHL reduces the quality of life of the growing population, setting seniors up for the enhanced mental decline. The size...