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Mark Li

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Articles 35
Citations 1197
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Recent Articles
1.
Verkerke A, Shi X, Li M, Higuchi Y, Yamamuro T, Katoh D, et al.
Cell Metab . 2024 Aug; 36(9):2156-2166.e9. PMID: 39111307
Choline is an essential nutrient for the biosynthesis of phospholipids, neurotransmitters, and one-carbon metabolism with a critical step being its import into mitochondria. However, the underlying mechanisms and biological significance...
2.
Qian Q, Li M, Zhang Z, Davis S, Rahmouni K, Norris A, et al.
Cell Metab . 2024 May; 36(7):1550-1565.e9. PMID: 38718793
Obesity alters levels of pituitary hormones that govern hepatic immune-metabolic homeostasis, dysregulation of which leads to nonalcoholic fatty liver disease (NAFLD). However, the impact of obesity on intra-pituitary homeostasis is...
3.
Balbach M, Axelrod M, Balko J, Bankhead A, Shaffer T, Lim L, et al.
Transl Lung Cancer Res . 2023 Mar; 12(2):257-265. PMID: 36895920
Background: Identifying a circulating biomarker predictive of immune checkpoint inhibitor (ICI) benefit in patients with small cell lung cancer (SCLC) remains an unmet need. Characteristics of peripheral and intratumoral T-cell...
4.
Jee J, Lebow E, Yeh R, Das J, Namakydoust A, Paik P, et al.
Nat Med . 2022 Nov; 28(11):2353-2363. PMID: 36357680
Circulating tumor DNA (ctDNA) sequencing guides therapy decisions but has been studied mostly in small cohorts without sufficient follow-up to determine its influence on overall survival. We prospectively followed an...
5.
Haseltine J, Offin M, Flynn J, Zhang Z, Lebow E, Aziz K, et al.
Transl Lung Cancer Res . 2022 Sep; 11(8):1578-1590. PMID: 36090640
Background: Cell free DNA (cfDNA) is an exciting biomarker with applications across the cancer care continuum. Determinants of cfDNA shedding dynamics remain an active research area. We performed a detailed...
6.
Li B, Daly B, Gospodarowicz M, Bertagnolli M, Brawley O, Chabner B, et al.
Nat Med . 2022 Apr; 28(4):620-626. PMID: 35440725
No abstract available.
7.
Sebag S, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, et al.
Cell Rep . 2021 Nov; 37(7):110003. PMID: 34788615
Brown adipose tissue (BAT) thermogenic activity is tightly regulated by cellular redox status, but the underlying molecular mechanisms are incompletely understood. Protein S-nitrosylation, the nitric-oxide-mediated cysteine thiol protein modification, plays...
8.
Zhao Y, Murciano-Goroff Y, Xue J, Ang A, Lucas J, Mai T, et al.
Nature . 2021 Nov; 599(7886):679-683. PMID: 34759319
Inactive state-selective KRAS(G12C) inhibitors demonstrate a 30-40% response rate and result in approximately 6-month median progression-free survival in patients with lung cancer. The genetic basis for resistance to these first-in-class...
9.
Maroun J, Li M, Oyefule O, El Badaoui J, McKenzie T, Kendrick M, et al.
Surg Endosc . 2021 Nov; 36(7):4946-4955. PMID: 34731300
Introduction: Bariatric surgery is the most effective modality to stably reduce weight and related comorbidities in patients suffering from class II and III obesity. Data comparing long-term safety and efficacy...
10.
Mondaca S, Lebow E, Namakydoust A, Razavi P, Reis-Filho J, Shen R, et al.
Lung Cancer . 2021 Oct; 162:210. PMID: 34625293
No abstract available.