Mark Jimenez
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Explore the profile of Mark Jimenez including associated specialties, affiliations and a list of published articles.
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Recent Articles
21.
Herrmann M, Harwood T, Gaston-Parry O, Kouzios D, Wong T, Lih A, et al.
Steroids
. 2010 Jul;
75(13-14):1106-12.
PMID: 20654641
Background: The accurate measurement of 25-hydoxy vitamin D (25OH-D) in serum has been a challenge for many years. We developed a liquid chromatography tandem mass spectrometry (LC Tandem MS) assay...
22.
Allan C, Couse J, Simanainen U, Spaliviero J, Jimenez M, Rodriguez K, et al.
Endocrinology
. 2010 Apr;
151(6):2800-10.
PMID: 20410197
Both testosterone and its nonaromatizable metabolite dihydrotestosterone (DHT) induce spermatogenesis in gonadotropin-deficient hpg mice. Surprisingly, because aromatization is not required, estradiol (E2) also induces spermatogenesis and increases circulating FSH in...
23.
Sertoli cell androgen receptor DNA binding domain is essential for the completion of spermatogenesis
Lim P, Robson M, Spaliviero J, McTavish K, Jimenez M, Zajac J, et al.
Endocrinology
. 2009 Jul;
150(10):4755-65.
PMID: 19574395
We examined the biological importance of Sertoli cell androgen receptor (AR) genomic interaction, using a Cre-loxP approach to selectively disrupt the AR DNA-binding domain (AR-DBD). Sertoli cell (SC)-specific transgenic Abpa...
24.
Handelsman D, Goebel C, Idan A, Jimenez M, Trout G, Kazlauskas R
Clin Endocrinol (Oxf)
. 2009 Jan;
71(3):417-28.
PMID: 19170708
Context: The administration of gonadotrophins is prohibited in sport but the effect in men of recently available recombinant hCG and LH on serum and urine concentrations of gonadotrophins and androgens...
25.
Lim P, Allan C, Notini A, Axell A, Spaliviero J, Jimenez M, et al.
Reprod Fertil Dev
. 2008 Nov;
20(8):861-70.
PMID: 19007549
Spermatogenesis requires androgen but, paradoxically, oestradiol (E2) treatment stimulates spermatogenic development in gonadotrophin- and androgen-deficient hypogonadal (hpg) mice. The mechanisms of E2-induced spermatogenesis were investigated by determining intratesticular E2 levels...
26.
McTavish K, Jimenez M, Walters K, Spaliviero J, Groome N, Themmen A, et al.
Endocrinology
. 2007 Jun;
148(9):4432-9.
PMID: 17540727
Rising serum FSH levels is one of the earliest signs of human female reproductive aging. Whether or not elevated FSH remains a passive reflection of a diminishing ovarian follicle pool...
27.
Korver W, Singh S, Liu S, Zhao X, Yonkovich S, Sweeney A, et al.
Br J Haematol
. 2007 Apr;
137(4):307-18.
PMID: 17456053
NTB-A is a CD2-related cell surface protein expressed primarily on lymphoid cells including B-lymphocytes from chronic lymphocytic leukaemia (CLL) and lymphoma patients. We have generated a series of monoclonal antibodies...
28.
Simanainen U, Allan C, Lim P, McPherson S, Jimenez M, Zajac J, et al.
Endocrinology
. 2007 Feb;
148(5):2264-72.
PMID: 17317769
Prostate development and maturation requires stromal-epithelial interactions and androgen action via the androgen receptor (AR) within these compartments. However, the specific roles of epithelial and stromal AR in postnatal prostate...
29.
Notini A, McManus J, Moore A, Bouxsein M, Jimenez M, Chiu W, et al.
J Bone Miner Res
. 2006 Dec;
22(3):347-56.
PMID: 17147488
Unlabelled: The mechanism of androgen action on bone was studied in male mice with the AR deleted in mature osteoblasts. These mice had decreased trabecular bone volume associated with a...
30.
Axell A, MacLean H, Plant D, Harcourt L, Davis J, Jimenez M, et al.
Am J Physiol Endocrinol Metab
. 2006 Apr;
291(3):E506-16.
PMID: 16621900
Androgens promote anabolism in skeletal muscle; however, effects on subsequent muscle function are less well defined because of a lack of reliable experimental models. We established a rigorous model of...