Mark Jimenez
Overview
Explore the profile of Mark Jimenez including associated specialties, affiliations and a list of published articles.
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40
Citations
807
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Recent Articles
1.
Walters K, Edwards M, Tesic D, Caldwell A, Jimenez M, Smith J, et al.
Neuroendocrinology
. 2018 Apr;
106(4):389-400.
PMID: 29635226
The androgen receptor (AR) is expressed throughout the hypothalamic-pituitary-gonadal (HPG) axis, and findings from female global AR knockout mice confirm that AR-mediated androgen actions play important roles in regulating female...
2.
Caldwell A, Edwards M, Desai R, Jimenez M, Gilchrist R, Handelsman D, et al.
Proc Natl Acad Sci U S A
. 2017 Mar;
114(16):E3334-E3343.
PMID: 28320971
Polycystic ovary syndrome (PCOS) is a complex hormonal disorder characterized by reproductive, endocrine, and metabolic abnormalities. As the origins of PCOS remain unknown, mechanism-based treatments are not feasible and current...
3.
Upton D, Walters K, Allavena R, Jimenez M, Desai R, Handelsman D, et al.
Horm Cancer
. 2016 Aug;
7(5-6):316-326.
PMID: 27506975
Phosphatase and tensin homologue (PTEN) is a known tumour suppressor. To explore the role of Pten in ovarian tumorigenesis, we used transgenic (Tg) SOX2. Cre and AMH. Cre mouse models...
4.
Hazra R, Upton D, Desai R, Noori O, Jimenez M, Handelsman D, et al.
Am J Physiol Endocrinol Metab
. 2016 Jun;
311(2):E396-404.
PMID: 27354237
Recently, we created a unique gain-of-function mouse model with Sertoli cell-specific transgenic androgen receptor expression (TgSCAR) showing that SCAR activity controls the synchronized postnatal development of somatic Sertoli and Leydig...
5.
Keski-Rahkonen P, Desai R, Jimenez M, Harwood D, Handelsman D
Anal Chem
. 2015 Jun;
87(14):7180-6.
PMID: 26090565
A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method is described that employs a novel derivatization reagent for the measurement of serum estradiol (E2), with simultaneous analysis of underivatized testosterone (T) and...
6.
Upton D, Fuller E, Colvin E, Walters K, Jimenez M, Desai R, et al.
Horm Cancer
. 2015 May;
6(4):142-52.
PMID: 25943777
BRCA1 mutations are associated with ovarian cancer. Previous studies reported that murine granulosa cell (GC) Brca1 loss caused ovarian-uterine tumors resembling serous cystadenomas, but the pathogenesis of these tumors may...
7.
Singh G, Balzer B, Desai R, Jimenez M, Steinbeck K, Handelsman D
Ann Clin Biochem
. 2015 Mar;
52(Pt 6):665-71.
PMID: 25780247
Objectives: Urinary hormone concentrations are often adjusted to correct for hydration status. We aimed to determine whether first morning void urine hormones in growing adolescents require adjustments and, if so,...
8.
Handelsman D, Jimenez M, Singh G, Spaliviero J, Desai R, Walters K
Endocrinology
. 2014 Nov;
156(1):400-5.
PMID: 25365769
Accurate measurement of testosterone is important for reproductive endocrinology research, but the validity of direct (nonextraction) testosterone immunoassays, developed and validated for human serum, has not been appraised for application...
9.
Singh G, Turner L, Desai R, Jimenez M, Handelsman D
J Clin Endocrinol Metab
. 2014 Apr;
99(7):2592-8.
PMID: 24684468
Context: Testosterone (T) and nandrolone (N) esters require deep im injections by medical personnel but these often deposit injectate into sc fat so that more convenient sc self-administration may be...
10.
Hazra R, Upton D, Jimenez M, Desai R, Handelsman D, Allan C
Endocrinology
. 2014 Jan;
155(3):1120-30.
PMID: 24424066
We determined the functional role of the Sertoli cell glucocorticoid receptor (GR) in vivo using a transgenic Cre-loxP approach to conditionally disrupt GR expression. Sertoli cell GR knockout (SCGRKO) was...