Mark J Jacobson
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Explore the profile of Mark J Jacobson including associated specialties, affiliations and a list of published articles.
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8
Citations
269
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Recent Articles
1.
Jacobson M, Lin G, Tepp W, Dupuy J, Stenmark P, Stevens R, et al.
Appl Environ Microbiol
. 2011 Apr;
77(12):4217-22.
PMID: 21515732
A Clostridium botulinum type A strain (A661222) in our culture collection was found to produce the botulinum neurotoxin subtype A5 (BoNT/A5). Its neurotoxin gene was sequenced to determine its degree...
2.
Lin G, Tepp W, Pier C, Jacobson M, Johnson E
Appl Environ Microbiol
. 2009 Nov;
76(1):40-7.
PMID: 19915042
Clostridium botulinum subtype A2 possesses a botulinum neurotoxin type A (BoNT/A) gene cluster consisting of an orfX cluster containing open reading frames (ORFs) of unknown functions. To better understand the...
3.
Iyer A, Blinkova A, Yang S, Harrison M, Tepp W, Jacobson M, et al.
Anaerobe
. 2009 Jan;
14(6):318-24.
PMID: 19135540
Clostridium taeniosporum is a Gram-positive, anaerobic, rod-shaped non-toxigenic organism isolated from Crimean lake silt. It is unique in forming spores from which about twelve large, flat, ribbon-like appendages emanate. These...
4.
Jacobson M, Lin G, Whittam T, Johnson E
Microbiology (Reading)
. 2008 Aug;
154(Pt 8):2408-2415.
PMID: 18667573
The genus Clostridium comprises a heterogeneous group of organisms for which the phylogeny and evolutionary relationships are poorly understood. The elucidation of these evolutionary relationships necessitates the use of experimental...
5.
Raphael B, Luquez C, McCroskey L, Joseph L, Jacobson M, Johnson E, et al.
Appl Environ Microbiol
. 2008 May;
74(14):4390-7.
PMID: 18502928
A group of five clonally related Clostridium botulinum type A strains isolated from different sources over a period of nearly 40 years harbored several conserved genetic properties. These strains contained...
6.
Jacobson M, Lin G, Raphael B, Andreadis J, Johnson E
Appl Environ Microbiol
. 2008 Mar;
74(9):2778-86.
PMID: 18326685
Neurotoxin cluster gene sequences and arrangements were elucidated for strains of Clostridium botulinum encoding botulinum neurotoxin (BoNT) subtypes A3, A4, and a unique A1-producing strain (HA(-) Orfx(+) A1). These sequences...
7.
Arndt J, Jacobson M, Abola E, Forsyth C, Tepp W, Marks J, et al.
J Mol Biol
. 2006 Aug;
362(4):733-42.
PMID: 16938310
Botulinum neurotoxin (BoNT) is a category A toxin that has been classified within seven serotypes, designated A-G. Recently, it has been discovered that sequence variability occurs in BoNTs produced by...
8.
Miyazaki M, Jacobson M, Man W, Cohen P, Asilmaz E, Friedman J, et al.
J Biol Chem
. 2003 Jun;
278(36):33904-11.
PMID: 12815040
Stearoyl-CoA desaturase (SCD) is the rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids. Thus far, three isoforms of SCD (SCD1, SCD2, and SCD3) have been identified and characterized. Regulation...