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Mark J Ferris

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Articles 41
Citations 1103
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Recent Articles
1.
Iacino M, Pitts E, Bonsib A, Sexton L, Ferris M
Drug Alcohol Depend . 2025 Jan; 268:112555. PMID: 39881470
Adolescence is a developmental period marked by significant alterations to brain neurobiology and behavior. Adolescent nicotine use disrupts developmental trajectories and increases vulnerability to maladaptive drug-taking in adulthood. The mesolimbic...
2.
Iacino M, Stowe T, Pitts E, Sexton L, Macauley S, Ferris M
Elife . 2024 Jun; 13. PMID: 38860652
Adolescence is characterized by changes in reward-related behaviors, social behaviors, and decision-making. These behavioral changes are necessary for the transition into adulthood, but they also increase vulnerability to the development...
3.
Davis S, Ferris M, Ananthan S, Augelli-Szafran C, Zhu J
J Pharmacol Exp Ther . 2022 Dec; 384(2):306-314. PMID: 36456195
Development of neurocognitive disorder in human immunodeficiency virus (HIV)-infected patients has been linked to dysregulation of dopamine by the HIV-1 transactivator of transcription (Tat) protein, a negative allosteric modulator of...
4.
Stowe T, Pitts E, Leach A, Iacino M, Niere F, Graul B, et al.
Cell Rep . 2022 Apr; 39(1):110633. PMID: 35385720
Dysregulation of biological rhythms plays a role in a wide range of psychiatric disorders. We report mechanistic insights into the rhythms of rapid dopamine signals and cholinergic interneurons (CINs) working...
5.
Leach A, Pitts E, Siciliano C, Ferris M
Eur J Neurosci . 2022 Feb; 55(5):1162-1173. PMID: 35141983
Heightened novelty-seeking phenotypes are associated with a range of behavioural traits including susceptibility to drug use. These relationships are recapitulated in preclinical models, where rats that exhibit increased exploratory activity...
6.
Burgos-Aguilar C, Ferris M, Sexton L, Sun H, Xiao R, Chen R, et al.
Synapse . 2020 Oct; 75(4):e22190. PMID: 33025628
Metabotropic glutamate (mGlu) receptors are regulators of glutamate release and targets for development of therapies for hyperactive glutamatergic signaling. However, the effects of long-term stimulation of mGlu receptors on cellular...
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Pitts E, Stowe T, Christensen B, Ferris M
Neuropharmacology . 2020 Jun; 175:108163. PMID: 32479812
Adolescence is characterized by changes in behavior, such as increases in sensation seeking and risk taking, and increased vulnerability to developing a range of psychiatric disorders, including substance abuse disorders...
9.
Chen R, Ferris M, Wang S
Pharmacol Ther . 2020 May; 213:107583. PMID: 32473160
Dopamine D2 autoreceptors (DARs), located in somatodendritic and axon terminal compartments of dopamine (DA) neurons, function to provide a negative feedback regulatory control on DA neuron firing, DA synthesis, reuptake...
10.
Fennell A, Pitts E, Sexton L, Ferris M
Sci Rep . 2020 Jan; 10(1):173. PMID: 31932634
Smoking remains the primary cause of preventable death in the United States and smoking related illness costs more than $300 billion annually. Nicotine (the primary reinforcer in cigarettes) causes changes...