Mark G Nilson
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Explore the profile of Mark G Nilson including associated specialties, affiliations and a list of published articles.
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5
Citations
24
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Recent Articles
1.
Chen H, Gurung S, Nieves-Quinones Y, Hruszkewycz D, Nilson M, Jakka K, et al.
J Org Chem
. 2024 Nov;
89(23):17408-17417.
PMID: 39528392
A critical step in the development of a convergent synthesis of an MRGPRX2 antagonist () was the S2 reaction with a highly functionalized lactamide electrophile and a unique difluoropiperidine nucleophile...
2.
Arrington K, Barcan G, Calandra N, Erickson G, Li L, Liu L, et al.
J Org Chem
. 2018 Oct;
84(8):4680-4694.
PMID: 30339385
A convergent eight-stage synthesis of the boron-containing NS5B inhibitor GSK8175 is described. The previous route involves 13 steps in a completely linear sequence, with an overall 10% yield. Key issues...
3.
Nilson M, Funk R
J Am Chem Soc
. 2011 Jul;
133(32):12451-3.
PMID: 21761900
A concise, diastereoselective total synthesis of (±)-cortistatin J has been completed in 20 steps from furan. Key steps include an intramolecular [4 + 3] cyclization of a disubstituted furan with...
4.
Nilson M, Funk R
Org Lett
. 2010 Oct;
12(21):4912-5.
PMID: 20932022
A concise diastereoselective total synthesis of (-)-nakadomarin A has been completed in 21 steps from D-pyroglutamic acid. Key steps include an enecarbamate Michael addition/furan-N-acyliminium ion cascade cyclization to provide the...
5.
Nilson M, Funk R
Org Lett
. 2006 Aug;
8(17):3833-6.
PMID: 16898829
[reaction: see text] The rapid construction of the tetracyclic core ring system of nakadomarin A via a tandem enecarbamate Michael addition/N-acyliminium ion cyclization is described.