Mark F McCarty
Overview
Explore the profile of Mark F McCarty including associated specialties, affiliations and a list of published articles.
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194
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2239
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Recent Articles
1.
Iloki Assanga S, Lewis Lujan L, McCarty M
Eur J Pharmacol
. 2023 Jul;
956:175898.
PMID: 37481200
Progressive up-regulation of β-catenin signaling is very common in the transformation of colorectal epithelium to colorectal cancer (CRC). Practical measures for opposing such signaling hence have potential for preventing or...
2.
McCarty M, Benzvi C, Vojdani A, Lerner A
Exp Dermatol
. 2023 Feb;
32(6):722-730.
PMID: 36811352
Ultraviolet B exposure to keratinocytes promotes carcinogenesis by inducing pyrimidine dimer lesions in DNA, suppressing the nucleotide excision repair mechanism required to fix them, inhibiting the apoptosis required for the...
3.
DiNicolantonio J, McCarty M, OKeefe J
Open Heart
. 2022 Dec;
9(2).
PMID: 36522127
The deacetylase sirtuin 1 (Sirt1), activated by calorie restriction and fasting, exerts several complementary effects on cellular function that are favourable to healthspan; it is often thought of as an...
4.
McCarty M, DiNicolantonio J, OKeefe J
Curr Issues Mol Biol
. 2022 Sep;
44(9):4314-4338.
PMID: 36135209
Oxidative and dicarbonyl stress, driven by excess accumulation of glycolytic intermediates in cells that are highly permeable to glucose in the absence of effective insulin activity, appear to be the...
5.
Lewis Lujan L, McCarty M, Di Nicolantonio J, Ruiz J, Rosas-Burgos E, Plascencia-Jatomea M, et al.
Nutrients
. 2022 May;
14(9).
PMID: 35565950
In patients with age-related macular degeneration (AMD), the crucial retinal pigment epithelial (RPE) cells are characterized by mitochondria that are structurally and functionally defective. Moreover, deficient expression of the mRNA-editing...
6.
McCarty M, Lewis Lujan L, Iloki Assanga S
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563167
There is a vast pre-clinical literature suggesting that certain nutraceuticals have the potential to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid treatment, chronic inflammation,...
7.
DiNicolantonio J, McCarty M, Iloki Assanga S, Lewis Lujan L, OKeefe J
Open Heart
. 2022 Mar;
9(1).
PMID: 35301252
Ferulic acid, a bacterial metabolite of anthocyanins, seems likely to be a primary mediator of the health benefits associated with anthocyanin-rich diets, and has long been employed in Chinese cardiovascular...
8.
DiNicolantonio J, McCarty M, OKeefe J
Open Heart
. 2022 Mar;
9(1).
PMID: 35296520
For reasons that remain unclear, endogenous synthesis and tissue levels of coenzyme Q10 (CoQ10) tend to decline with increasing age in at least some tissues. When CoQ10 levels are sufficiently...
9.
McCarty M
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216170
Macroautophagy is a "cell cleansing" process that rids cells of protein aggregates and damaged organelles that may contribute to disease pathogenesis and the dysfunctions associated with aging. Measures which boost...
10.
McCarty M, DiNicolantonio J
Healthcare (Basel)
. 2022 Jan;
10(1).
PMID: 35052168
In people with metabolic syndrome, episodic exposure of pancreatic beta cells to elevated levels of both glucose and free fatty acids (FFAs)-or glucolipotoxicity-can induce a loss of glucose-stimulated insulin secretion...