Mark E Haskins
Overview
Explore the profile of Mark E Haskins including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
75
Citations
1786
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Peck S, Lau Y, Kang J, Lin M, Arginteanu T, Matalon D, et al.
Mol Genet Metab
. 2021 Jun;
133(4):378-385.
PMID: 34154922
Mucopolysaccharidosis (MPS) VII is a lysosomal storage disorder characterized by deficient β-glucuronidase activity, leading to accumulation of incompletely degraded heparan, dermatan and chondroitin sulfate glycosaminoglycans. Patients with MPS VII exhibit...
2.
Ferla R, Alliegro M, DellAnno M, Nusco E, Cullen J, Smith S, et al.
Mol Ther Methods Clin Dev
. 2021 Jan;
20:247-257.
PMID: 33473358
Adeno-associated viral (AAV) vectors have emerged as the preferred platform for gene transfer because of their combined efficacy and safety. However, insertional mutagenesis with the subsequent development of hepatocellular carcinomas...
3.
Peck S, Tobias J, Shore E, Malhotra N, Haskins M, Casal M, et al.
Bone
. 2019 Aug;
128:115042.
PMID: 31442675
Mucopolysaccharidosis (MPS) VII is a lysosomal storage disorder characterized by deficient activity of β-glucuronidase, leading to progressive accumulation of incompletely degraded heparan, dermatan, and chondroitin sulfate glycosaminoglycans (GAGs). Patients with...
4.
Scarpa M, Orchard P, Schulz A, Dickson P, Haskins M, Escolar M, et al.
Mol Genet Metab
. 2017 Nov;
122S:25-34.
PMID: 29153844
The mucopolysaccharidosis (MPS) disorders are a group of lysosomal storage diseases caused by lysosomal enzyme deficits that lead to glycosaminoglycan accumulation, affecting various tissues throughout the body based on the...
5.
Hinderer C, Bell P, Katz N, Vite C, Louboutin J, Bote E, et al.
Hum Gene Ther
. 2017 Aug;
29(1):15-24.
PMID: 28806897
Delivery of adeno-associated viral (AAV) vectors into the cerebrospinal fluid (CSF) can achieve gene transfer to cells throughout the brain and spinal cord, potentially making many neurological diseases tractable gene...
6.
Toromanoff A, Cherel Y, Guilbaud M, Penaud-Budloo M, Snyder R, Haskins M, et al.
Mol Ther
. 2017 Feb;
16(7):1291-1299.
PMID: 28178483
We developed a drug-free regional intravenous (RI) delivery protocol of recombinant adeno-associated virus (rAAV) 1 and 8 to an entire limb in the nonhuman primate (NHP), and compared the results...
7.
Neonatal tolerance induction enables accurate evaluation of gene therapy for MPS I in a canine model
Hinderer C, Bell P, Louboutin J, Katz N, Zhu Y, Lin G, et al.
Mol Genet Metab
. 2016 Jul;
119(1-2):124-30.
PMID: 27386755
High fidelity animal models of human disease are essential for preclinical evaluation of novel gene and protein therapeutics. However, these studies can be complicated by exaggerated immune responses against the...
8.
Simonaro C, Tomatsu S, Sikora T, Kubaski F, Frohbergh M, Guevara J, et al.
PLoS One
. 2016 Apr;
11(4):e0153136.
PMID: 27064989
Background: We previously demonstrated the therapeutic benefits of pentosan polysulfate (PPS) in a rat model of mucopolysaccharidosis (MPS) type VI. Reduction of inflammation, reduction of glycosaminoglycan (GAG) storage, and improvement...
9.
Pang B, Yee K, Lischka F, Rawson N, Haskins M, Wysocki C, et al.
J Exp Biol
. 2016 Apr;
219(Pt 12):1866-74.
PMID: 27045093
The surface area of the maxilloturbinals and fronto-ethmoturbinals is commonly used as an osteological proxy for the respiratory and the olfactory epithelium, respectively. However, this assumption does not fully account...
10.
Callan M, Haskins M, Wang P, Zhou S, High K, Arruda V
PLoS One
. 2016 Mar;
11(3):e0151800.
PMID: 27011017
Severe hemophilia A (HA) is an inherited bleeding disorder characterized by <1% of residual factor VIII (FVIII) clotting activity. The disease affects several mammals including dogs, and, like humans, is...