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Mark de Caestecker

Explore the profile of Mark de Caestecker including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 1036
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Recent Articles
1.
Esselman A, Moser F, Tideman L, Migas L, Djambazova K, Colley M, et al.
Kidney Int . 2024 Nov; 107(2):332-337. PMID: 39571907
Glomeruli filter blood through the coordination of podocytes, mesangial cells, fenestrated endothelial cells, and the glomerular basement membrane. Cellular changes, such as podocyte loss, are associated with pathologies like diabetic...
2.
Vanichapol T, Gonzalez A, Delgado R, Brewer M, Clouthier K, Menshikh A, et al.
bioRxiv . 2024 Sep; PMID: 39314319
Summary: Partial repair after reversal of urinary obstruction leads to permanent changes in structure and function of all major cellular compartments in the renal papilla.
3.
Hammoud S, Ivanova A, Osaki Y, Funk S, Yang H, Viquez O, et al.
JCI Insight . 2024 May; 9(9). PMID: 38716735
No abstract available.
4.
Hammoud S, Ivanova A, Osaki Y, Funk S, Yang H, Viquez O, et al.
JCI Insight . 2024 Mar; 9(6). PMID: 38516886
Kidney tubules use fatty acid oxidation (FAO) to support their high energetic requirements. Carnitine palmitoyltransferase 1A (CPT1A) is the rate-limiting enzyme for FAO, and it is necessary to transport long-chain...
5.
Yang M, Lopez L, Brewer M, Delgado R, Menshikh A, Clouthier K, et al.
JCI Insight . 2023 Sep; 8(20. PMID: 37698919
Retinoic acid receptor (RAR) signaling is essential for mammalian kidney development but, in the adult kidney, is restricted to occasional collecting duct epithelial cells. We now show that there is...
6.
Hyndman K, Hukriede N, de Caestecker M
Semin Nephrol . 2022 Nov; 42(3):151275. PMID: 36402655
No abstract available.
7.
Long K, Vaughn Z, McDaniels M, Joyasawal S, Przepiorski A, Parasky E, et al.
ACS Pharmacol Transl Sci . 2022 Apr; 5(4):207-215. PMID: 35434532
Acute kidney injury (AKI), a sudden loss of kidney function, is a common and serious condition for which there are no approved specific therapies. While there are multiple approaches to...
8.
Borza C, Bolas G, Bock F, Zhang X, Akabogu F, Zhang M, et al.
JCI Insight . 2021 Dec; 7(3. PMID: 34941574
Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase activated by collagen, contributes to chronic kidney disease. However, its role in acute kidney injury and subsequent development of kidney fibrosis...
9.
De La Cruz L, Yang X, Menshikh A, Brewer M, Lu W, Wang M, et al.
Chem Sci . 2021 Aug; 12(31):10649-10654. PMID: 34447558
Carbon monoxide as an endogenous signaling molecule exhibits pharmacological efficacy in various animal models of organ injury. To address the difficulty in using CO gas as a therapeutic agent for...
10.
de Caestecker M
Am J Physiol Renal Physiol . 2020 Oct; 319(5):F865-F867. PMID: 33073588
No abstract available.