Mark de Caestecker
Overview
Explore the profile of Mark de Caestecker including associated specialties, affiliations and a list of published articles.
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37
Citations
1036
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Recent Articles
11.
Terker A, de Caestecker M
Kidney Int
. 2020 Jan;
97(1):22-24.
PMID: 31901349
Matsushita et al. describe a model of acute kidney injury to chronic kidney disease progression in mice surviving cardiac arrest: mice develop severe acute kidney injury that initially recovers but...
12.
Yang X, de Caestecker M, Otterbein L, Wang B
Med Res Rev
. 2019 Dec;
40(4):1147-1177.
PMID: 31820474
Treating acute kidney injury (AKI) represents an important unmet medical need both in terms of the seriousness of this medical problem and the number of patients. There is also a...
13.
Scarfe L, Schock-Kusch D, Ressel L, Friedemann J, Shulhevich Y, Murray P, et al.
J Vis Exp
. 2018 Nov;
(140).
PMID: 30394397
Transdermal analysis of glomerular filtration rate (GFR) is an established technique that is used to assess renal function in mouse and rat models of acute kidney injury and chronic kidney...
14.
Zuk A, Palevsky P, Fried L, Harrell Jr F, Khan S, McKay D, et al.
Clin J Am Soc Nephrol
. 2018 Mar;
13(7):1113-1123.
PMID: 29523680
AKI is a complex clinical condition associated with high mortality, morbidity, and health care costs. Despite improvements in methodology and design of clinical trials, and advances in understanding the underlying...
15.
de Caestecker M, Harris R
Semin Nephrol
. 2018 Jan;
38(1):88-97.
PMID: 29291764
No therapies have been shown to improve outcomes in patients with acute kidney injury (AKI). Given the high morbidity and mortality associated with AKI this represents an important unmet medical...
16.
Hukriede N, Vogt A, de Caestecker M
Nephron
. 2017 Jun;
137(4):268-272.
PMID: 28614822
The cellular responses that occur following acute kidney injury (AKI) are complex and dynamic, involving multiple cells types and molecular pathways. For this reason, early selection of defined molecular targets...
17.
King T, de Caestecker M, Lowery J
Surg Neurol Int
. 2016 Nov;
7:91.
PMID: 27857855
No abstract available.
18.
West J, Voss B, Pavliv L, de Caestecker M, Hemnes A, Carrier E
Pulm Circ
. 2016 Jun;
6(2):211-23.
PMID: 27252848
Right ventricular (RV) failure is the primary cause of death in pulmonary arterial hypertension (PAH) and is a significant cause of morbidity and mortality in other forms of pulmonary hypertension....
19.
de Caestecker M, Humphreys B, Liu K, Fissell W, Cerda J, Nolin T, et al.
J Am Soc Nephrol
. 2015 Nov;
26(12):2905-16.
PMID: 26538634
Despite extensive research, no therapeutic interventions have been shown to prevent AKI, accelerate recovery of AKI, or reduce progression of AKI to CKD in patients. This failure in translation has...
20.
Pierce J, Murphy A, Panzer A, de Caestecker C, Ayers G, Neblett D, et al.
Transl Oncol
. 2014 Dec;
7(6):800-11.
PMID: 25500091
Wilms tumor (WT) blastema retains gene expression profiles characteristic of the multipotent nephron progenitor pool, or cap mesenchyme (CM), in the developing kidney. As a result, WT blastema and the...