» Authors » Mark D Zarella

Mark D Zarella

Explore the profile of Mark D Zarella including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 516
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Macaulay D, Han W, Zarella M, Garcia C, Tavolara T
J Pathol Clin Res . 2025 Mar; 11(2):e70024. PMID: 40050230
Breast cancer affects millions globally, necessitating precise biomarker testing for effective treatment. HER2 testing is crucial for guiding therapy, particularly with novel antibody-drug conjugates (ADCs) like trastuzumab deruxtecan, which shows...
2.
Zarella M, McClintock D, Batra H, Gullapalli R, Valante M, Tan V, et al.
J Med Imaging (Bellingham) . 2023 Aug; 10(5):051802. PMID: 37528811
Artificial intelligence (AI) presents an opportunity in anatomic pathology to provide quantitative objective support to a traditionally subjective discipline, thereby enhancing clinical workflows and enriching diagnostic capabilities. AI requires access...
3.
Zarella M, Rivera Alvarez K
J Pathol . 2022 May; 257(4):383-390. PMID: 35511469
Digital pathology and artificial intelligence (AI) rely on digitization of patient material as a necessary first step. AI development benefits from large sample sizes and diverse cohorts, and therefore efforts...
4.
Lujan G, Quigley J, Hartman D, Parwani A, Roehmholdt B, Van Meter B, et al.
J Pathol Inform . 2021 Jul; 12:17. PMID: 34221633
We believe the switch to a digital pathology (DP) workflow is imminent and it is essential to understand the economic implications of conversion. Many aspects of the adoption of DP...
5.
White M, Birkness J, Salimian K, Meiss A, Butcher M, Davis K, et al.
Arch Pathol Lab Med . 2021 Mar; 145(7):814-820. PMID: 33740819
Context.—: In the early months of the response to the coronavirus disease 2019 (COVID-19) pandemic, the Johns Hopkins University School of Medicine (JHUSOM) (Baltimore, Maryland) leadership reached out to faculty...
6.
Lara H, Li Z, Abels E, Aeffner F, Bui M, ElGabry E, et al.
Appl Immunohistochem Mol Morphol . 2021 Mar; 29(7):479-493. PMID: 33734106
Tissue biomarkers have been of increasing utility for scientific research, diagnosing disease, and treatment response prediction. There has been a steady shift away from qualitative assessment toward providing more quantitative...
7.
Zarella M, Jakubowski J
J Med Imaging (Bellingham) . 2020 Jan; 6(4):047502. PMID: 31890747
Digital screening and diagnosis from cytology slides can be aided by capturing multiple focal planes. However, using conventional methods, the large file sizes of high-resolution whole-slide images increase linearly with...
8.
Abels E, Pantanowitz L, Aeffner F, Zarella M, van der Laak J, Bui M, et al.
J Pathol . 2019 Jul; 249(3):286-294. PMID: 31355445
In this white paper, experts from the Digital Pathology Association (DPA) define terminology and concepts in the emerging field of computational pathology, with a focus on its application to histology...
9.
Aeffner F, Zarella M, Buchbinder N, Bui M, Goodman M, Hartman D, et al.
J Pathol Inform . 2019 Apr; 10:9. PMID: 30984469
The advent of whole-slide imaging in digital pathology has brought about the advancement of computer-aided examination of tissue via digital image analysis. Digitized slides can now be easily annotated and...
10.
Zarella M, Feldscher A
J Pathol Inform . 2019 Jan; 9:44. PMID: 30622834
Background: In an effort to provide improved user experience and system reliability at a moderate cost, our department embarked on targeted upgrades of a total of 87 computers over a...