Mark C Thel
Overview
Explore the profile of Mark C Thel including associated specialties, affiliations and a list of published articles.
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7
Citations
111
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Recent Articles
1.
Horitani K, Chavkin N, Arai Y, Wang Y, Ogawa H, Yura Y, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(3):343-355.
PMID: 39183958
Heart failure affects millions of people worldwide, with men exhibiting a higher incidence than women. Our previous work has shown that mosaic loss of the Y chromosome (LOY) in leukocytes...
2.
Thel M, Cochran J, Teruya S, Hayashi O, Xie C, Srinivasan A, et al.
Circ Heart Fail
. 2024 Jun;
17(8):e011681.
PMID: 38853760
No abstract available.
3.
Cochran J, Yura Y, Thel M, Doviak H, Polizio A, Arai Y, et al.
Circulation
. 2023 Sep;
148(15):1165-1178.
PMID: 37681311
Background: Clonal hematopoiesis (CH), which results from an array of nonmalignant driver gene mutations, can lead to altered immune cell function and chronic disease, and has been associated with worse...
4.
Sano S, Thel M, Walsh K
Physiology (Bethesda)
. 2023 Mar;
38(4).
PMID: 36976266
We present a brief introduction of loss of Y chromosome (LOY) in blood and describe the known risk factors for this condition. We then overview the associations between LOY and...
5.
Sano S, Thel M, Walsh K
Curr Opin Cardiol
. 2023 Feb;
38(3):201-206.
PMID: 36811645
Purpose Of Review: Somatic mutations, described as noninherited changes in DNA that arise and are passed on to descendant cells, are well known to cause cancers; however, it is increasingly...
6.
Min K, Polizio A, Kour A, Thel M, Walsh K
J Am Heart Assoc
. 2022 Sep;
11(19):e026154.
PMID: 36129058
No abstract available.
7.
Sano S, Horitani K, Ogawa H, Halvardson J, Chavkin N, Wang Y, et al.
Science
. 2022 Jul;
377(6603):292-297.
PMID: 35857592
Hematopoietic mosaic loss of Y chromosome (mLOY) is associated with increased risk of mortality and age-related diseases in men, but the causal and mechanistic relationships have yet to be established....