Mark Bradley
Overview
Explore the profile of Mark Bradley including associated specialties, affiliations and a list of published articles.
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Articles
291
Citations
4161
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Recent Articles
1.
Baibek A, Konieczna Z, Ucuncu M, Alghamdi Z, Sharma R, Horrocks M, et al.
Chem Biomed Imaging
. 2025 Jan;
3(1):45-50.
PMID: 39886222
Bacterial resistance, primarily stemming from misdiagnosis, misuse, and overuse of antibacterial medications in humans and animals, is a pressing issue. To address this, we focused on developing a fluorescent probe...
2.
Sharma R, Rodriguez-Rios M, Crossland J, Septiyana M, Megia-Fernandez A, Klausen M, et al.
J Mater Chem B
. 2024 Dec;
13(3):882-887.
PMID: 39717883
A multi-branched fluorogenic probe for the rapid and specific detection of Gram-negative bacteria is reported. Three Gram-negative-targeting azido-modified polymyxins were clicked onto a trivalent scaffold functionalised with the environmental green-emitting...
3.
Colvin L, Al Husseini D, Tu D, Dunlap D, Lalonde T, Ucuncu M, et al.
ACS Sens
. 2024 Nov;
9(11):6218-6227.
PMID: 39536779
Deep-red fluorescence was implemented in this fully injectable, nonenzymatic glucose biosensor design to allow for better light penetration through the skin, particularly for darker skin tones. In this work, a...
4.
Alghamdi Z, Sharma R, Kiruthiga N, Ucuncu M, Klausen M, Santra M, et al.
Org Biomol Chem
. 2024 Oct;
22(44):8781-8786.
PMID: 39397698
We report a series of fluorescent probes based on mycobacteria membrane-associated disruption peptide, containing either L- or D-amino acids which were originally designed to kill membrane disruption. These peptides were...
5.
Perasoli F, B Silva L, C Figueiredo B, Pinto I, F Amaro L, S Almeida Bastos J, et al.
Nanomedicine (Lond)
. 2024 May;
19(14):1285-1296.
PMID: 38722243
To investigate whether medical devices coated with a synthesized nanocomposite of poly(methylmethacrylate-co-dimethyl acrylamide) (PMMDMA) and silver nanoparticles (AgNPs) could improve their antibiofilm and antimicrobial activities. We also investigated the nanocomposite's...
6.
Abdelrahim M, Gao Q, Zhang Y, Li W, Xing Q, Bradley M, et al.
Nat Protoc
. 2024 Mar;
19(7):1984-2025.
PMID: 38514838
The synthesis of synthetic intracellular polymers offers groundbreaking possibilities in cellular biology and medical research, allowing for novel experiments in drug delivery, bioimaging and targeted cancer therapies. These macromolecules, composed...
7.
Shaw P, Klausen M, Bradley M
Polym Chem
. 2024 Jan;
15(2):54-58.
PMID: 38174055
A light-responsive polymer allowing the controlled release of camptothecin and the generation of reactive oxygen species (ROS) is reported. The polymer was prepared by controlled copolymerisation of water-soluble ,-dimethyl acrylamide...
8.
Haseeb F, Bourdakos K, Forsyth E, Setchfield K, Gorman A, Venkateswaran S, et al.
J Biomed Opt
. 2023 Dec;
28(12):126007.
PMID: 38155703
Significance: Rapid advances in medical imaging technology, particularly the development of optical systems with non-linear imaging modalities, are boosting deep tissue imaging. The development of reliable standards and phantoms is...
9.
Mills B, Kiang A, Mohanan S, Bradley M, Klausen M
JACS Au
. 2023 Nov;
3(11):3014-3023.
PMID: 38034955
Decades of antibiotic misuse have led to alarming levels of antimicrobial resistance, and the development of alternative diagnostic and therapeutic strategies to delineate and treat infections is a global priority....
10.
Rodriguez-Rios M, McHugh B, Liang Z, Megia-Fernandez A, Lilienkampf A, Dockrell D, et al.
Commun Chem
. 2023 Nov;
6(1):237.
PMID: 37919467
Cathepsin D is a protease that is an effector in the immune response of macrophages, yet to date, only a limited number of probes have been developed for its detection....