Mark A Miles
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Explore the profile of Mark A Miles including associated specialties, affiliations and a list of published articles.
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30
Citations
207
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Recent Articles
1.
Nturubika B, Logan J, Johnson I, Moore C, Li K, Tang J, et al.
Cancers (Basel)
. 2025 Jan;
17(1.
PMID: 39796673
Prostate cancer remains a significant global health concern, with over 1.4 million new cases diagnosed and more than 330,000 deaths each year. The primary clinical challenge that contributes to poor...
2.
Miles M, Liong S, Liong F, Trollope G, Wang H, Brooks R, et al.
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769461
Severe lower respiratory tract disease following influenza A virus (IAV) infection is characterized by excessive inflammation and lung tissue damage, and this can impair lung function. The effect of toll-like...
3.
Hindes M, McElligott A, Best O, Ward M, Selemidis S, Miles M, et al.
Cancer Lett
. 2025 Jan;
611():217441.
PMID: 39755364
Metabolic reprogramming is a hallmark of cancer, crucial for malignant transformation and metastasis. Chronic lymphocytic leukaemia (CLL) and prostate cancer exhibit similar metabolic adaptations, particularly in glucose and lipid metabolism....
4.
Liong S, Liong F, Mohsenipour M, Hill-Yardin E, Miles M, Selemidis S
Cells
. 2024 Oct;
13(20.
PMID: 39451246
Severe respiratory syncytial virus (RSV) infection during early life has been linked to gut dysbiosis, which correlates with increased disease severity and a higher risk of developing asthma later in...
5.
Oseghale O, Quinn K, Coward-Smith M, Liong F, Miles M, Brooks R, et al.
Am J Physiol Heart Circ Physiol
. 2024 Sep;
327(4):H967-H977.
PMID: 39240256
T-cell accumulation within the aorta promotes endothelial dysfunction and the genesis of cardiovascular disease, including hypertension and atherosclerosis. Viral infection during pregnancy is also known to mediate marked acute endothelial...
6.
Liong S, Choy K, De Luca S, Liong F, Coward-Smith M, Oseghale O, et al.
Brain Behav Immun
. 2024 Jun;
120:488-498.
PMID: 38925418
Influenza A virus (IAV) infection during pregnancy can increase the risk for neurodevelopmental disorders in the offspring, however, the underlying neurobiological mechanisms are largely unknown. To recapitulate viral infection, preclinical...
7.
Coward-Smith M, Liong S, Oseghale O, Erlich J, Miles M, Liong F, et al.
Front Immunol
. 2024 Apr;
15:1378610.
PMID: 38638436
Influenza A virus (IAV) infection in pregnancy resembles a preeclamptic phenotype characterised by vascular dysfunction and foetal growth retardation. Given that low dose aspirin (ASA) is safe in pregnancy and...
8.
Miles M, Luong R, To E, Erlich J, Liong S, Liong F, et al.
Cells
. 2024 Jan;
13(1).
PMID: 38201300
Prostate cancer is ranked second in the world for cancer-related deaths in men, highlighting the lack of effective therapies for advanced-stage disease. Toll-like receptors (TLRs) and immunity have a direct...
9.
Miles M, Liong S, Liong F, Coward-Smith M, Trollope G, Oseghale O, et al.
Front Immunol
. 2023 Oct;
14:1240552.
PMID: 37795093
Respiratory syncytial virus (RSV) commonly infects the upper respiratory tract (URT) of humans, manifesting with mild cold or flu-like symptoms. However, in infants and the elderly, severe disease of the...
10.
Tencer A, Yu Y, Causse S, Campbell G, Klein B, Xuan H, et al.
Nat Struct Mol Biol
. 2023 Jul;
30(9):1265-1274.
PMID: 37524969
The inhibitor of apoptosis protein BIRC2 regulates fundamental cell death and survival signaling pathways. Here we show that BIRC2 accumulates in the nucleus via binding of its second and third...