Mark A Herman
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Explore the profile of Mark A Herman including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Abushamat L, Yu B, Hoogeveen R, Sun C, Cheng C, Hartig S, et al.
JACC Adv
. 2025 Feb;
4(3):101605.
PMID: 39983608
Background: Circulating erythritol, an endogenously produced metabolite and an artificial sweetener, is associated with cardiovascular outcomes. Objectives: The authors assessed associations of erythritol and its downstream metabolite, erythronate, with cardiovascular...
2.
Calhoun P, Spanbauer C, Steck A, Frohnert B, Herman M, Keymeulen B, et al.
Diabetologia
. 2025 Feb;
PMID: 39934369
Aims/hypothesis: We aimed to assess whether continuous glucose monitor (CGM) metrics can accurately predict stage 3 type 1 diabetes diagnosis in those with islet autoantibodies (AAb). Methods: Baseline CGM data...
3.
An J, Astapova I, Zhang G, Cangelosi A, Ilkayeva O, Marchuk H, et al.
Cell Rep
. 2025 Feb;
44(2):115278.
PMID: 39921857
The transcription factor carbohydrate response element binding protein (ChREBP) activates genes of glucose, fructose, and lipid metabolism in response to carbohydrate feeding. Integrated transcriptomic and metabolomic analyses in rats with...
4.
Hartig S, Herman M
Cell Metab
. 2025 Jan;
37(1):3-4.
PMID: 39778518
De novo lipogenesis (DNL) is the process whereby cells synthesize fatty acids from acetyl-CoA, contributing to steatosis in fatty liver disease. Two new studies, using genetic mouse models, metabolomics, and...
5.
Tiwari V, Jin B, Sun O, Lopez Gonzalez E, Chen M, Wu X, et al.
bioRxiv
. 2025 Jan;
PMID: 39763913
Citrin Deficiency (CD) is caused by inactivation of SLC25A13, a mitochondrial membrane protein required to move electrons from cytosolic NADH to the mitochondrial matrix in hepatocytes. People with CD do...
6.
An J, Astapova I, Zhang G, Cangelosi A, Ilkayeva O, Marchuk H, et al.
bioRxiv
. 2024 Sep;
PMID: 39345566
Carbohydrate Response Element-Binding Protein (ChREBP) is a transcription factor that activates key genes involved in glucose, fructose, and lipid metabolism in response to carbohydrate feeding, but its other potential roles...
7.
Tong W, Hannou S, Sargsyan A, Zhang G, Grimsrud P, Astapova I, et al.
bioRxiv
. 2023 May;
PMID: 37131695
Objective: To investigate the effects of metformin on intestinal carbohydrate metabolism . Method: Male mice preconditioned with a high-fat, high-sucrose diet were treated orally with metformin or a control solution...
8.
Haslam D, Chasman D, Peloso G, Herman M, Dupuis J, Lichtenstein A, et al.
J Nutr
. 2023 Feb;
152(11):2534-2545.
PMID: 36774119
Background: Prospective cohort studies have found a relation between sugar-sweetened beverage (SSB) consumption (sodas and fruit drinks) and dyslipidemia. There is limited evidence linking SSB consumption to emerging features of...
9.
Wang L, Tang Y, Herman M, Spurney R
Transl Res
. 2022 Dec;
255:140-151.
PMID: 36563959
While natriuretic peptides (NPs) are primarily known for their renal and cardiovascular actions, NPs stimulate lipolysis in adipocytes and induce a thermogenic program in white adipose tissue (WAT) that resembles...
10.
Sargsyan A, Doridot L, Hannou S, Tong W, Srinivasan H, Ivison R, et al.
JCI Insight
. 2022 Nov;
8(1).
PMID: 36413406
Carbohydrate response element-binding protein (ChREBP) is a carbohydrate-sensing transcription factor that regulates both adaptive and maladaptive genomic responses in coordination of systemic fuel homeostasis. Genetic variants in the ChREBP locus...