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Marja van Eggermond

Explore the profile of Marja van Eggermond including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 79
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Recent Articles
1.
Sorel N, Diaz-Pascual F, Bessot B, Sadek H, Mollet C, Chouteau M, et al.
Biomedicines . 2024 Jul; 12(7). PMID: 39062069
Recombinase-activating gene (RAG)-deficient SCID patients lack B and T lymphocytes due to the inability to rearrange immunoglobulin and T cell receptor genes. The two genes act as a required dimer...
2.
Garcia-Perez L, Famili F, Cordes M, Brugman M, van Eggermond M, Wu H, et al.
Sci Adv . 2020 Aug; 6(31):eaaw7313. PMID: 32789164
T cell factor 1 (Tcf1) is the first T cell-specific protein induced by Notch signaling in the thymus, leading to the activation of two major target genes, and . Tcf1...
3.
Garcia-Perez L, van Eggermond M, van Roon L, Vloemans S, Cordes M, Schambach A, et al.
Mol Ther Methods Clin Dev . 2020 Apr; 17:666-682. PMID: 32322605
Recombinase-activating gene-1 (RAG1)-deficient severe combined immunodeficiency (SCID) patients lack B and T lymphocytes due to the inability to rearrange immunoglobulin and T cell receptor genes. Gene therapy is an alternative...
4.
Cordes M, Pike-Overzet K, van Eggermond M, Vloemans S, Baert M, Garcia-Perez L, et al.
Bioinformatics . 2019 Oct; PMID: 31665245
Summary: An effective immune system is characterized by a diverse immune repertoire. There is a strong demand for accurate and quantitative methods to assess the diversity of the immune repertoire...
5.
Brugman M, Wiekmeijer A, van Eggermond M, Wolvers-Tettero I, Langerak A, de Haas E, et al.
Proc Natl Acad Sci U S A . 2015 Oct; 112(44):E6020-7. PMID: 26483497
The fate and numbers of hematopoietic stem cells (HSC) and their progeny that seed the thymus constitute a fundamental question with important clinical implications. HSC transplantation is often complicated by...