Chantal Lagresle-Peyrou
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Explore the profile of Chantal Lagresle-Peyrou including associated specialties, affiliations and a list of published articles.
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42
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706
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Recent Articles
1.
Martin Corredera M, Paillet J, Gaudeaux P, Blein T, Sadek H, Rault P, et al.
Front Immunol
. 2025 Mar;
16:1531736.
PMID: 40051631
Introduction: Natural Killer (NK) cells hold significant promise as therapeutic agents in immuno-oncology due to their ability to target and eliminate cancerous and infected cells without causing graft-versus-host disease or...
2.
Garrigue A, Kermasson L, Susini S, Fert I, Mahony C, Sadek H, et al.
J Clin Invest
. 2025 Jan;
PMID: 39847438
Oncostatin M (OSM) is a cytokine with the unique ability to interact with both the OSM receptor (OSMR) and the leukemia inhibitory factor receptor (LIFR). On the other hand, OSMR...
3.
Bohlen J, Bagaric I, Vatovec T, Ogishi M, Ahmed S, Cederholm A, et al.
J Clin Invest
. 2024 Oct;
134(20).
PMID: 39403923
Patients heterozygous for germline CBL loss-of-function (LOF) variants can develop myeloid malignancy, autoinflammation, or both, if some or all of their leukocytes become homozygous for these variants through somatic loss...
4.
Benavides-Nieto M, Adam F, Martin E, Boussard C, Lagresle-Peyrou C, Callebaut I, et al.
J Clin Invest
. 2024 Sep;
134(17).
PMID: 39225097
The ubiquitously expressed small GTPase Ras-related protein 1B (RAP1B) acts as a molecular switch that regulates cell signaling, cytoskeletal remodeling, and cell trafficking and activates integrins in platelets and lymphocytes....
5.
Doye A, Chaintreuil P, Lagresle-Peyrou C, Batistic L, Marion V, Munro P, et al.
J Exp Med
. 2024 Aug;
221(10).
PMID: 39212656
A growing number of patients presenting severe combined immunodeficiencies attributed to monoallelic RAC2 variants have been identified. The expression of the RHO GTPase RAC2 is restricted to the hematopoietic lineage....
6.
Sorel N, Diaz-Pascual F, Bessot B, Sadek H, Mollet C, Chouteau M, et al.
Biomedicines
. 2024 Jul;
12(7).
PMID: 39062069
Recombinase-activating gene (RAG)-deficient SCID patients lack B and T lymphocytes due to the inability to rearrange immunoglobulin and T cell receptor genes. The two genes act as a required dimer...
7.
Momenilandi M, Levy R, Sobrino S, Li J, Lagresle-Peyrou C, Esmaeilzadeh H, et al.
Cell
. 2024 May;
187(11):2817-2837.e31.
PMID: 38701783
FMS-related tyrosine kinase 3 ligand (FLT3L), encoded by FLT3LG, is a hematopoietic factor essential for the development of natural killer (NK) cells, B cells, and dendritic cells (DCs) in mice....
8.
Ito Y, Marouf A, Kogure Y, Koya J, Lievin R, Bruneau J, et al.
Cancer Res
. 2024 Apr;
84(13):2181-2201.
PMID: 38657099
Extranodal NK/T-cell lymphoma (ENKTCL) is an Epstein-Barr virus (EBV)-related neoplasm with male dominance and a poor prognosis. A better understanding of the genetic alterations and their functional roles in ENKTCL...
9.
Donko A, Sharapova S, Kabat J, Ganesan S, Hauck F, Bergerson J, et al.
Blood
. 2024 Jan;
143(15):1476-1487.
PMID: 38194689
Mutations in the small Rho-family guanosine triphosphate hydrolase RAC2, critical for actin cytoskeleton remodeling and intracellular signal transduction, are associated with neonatal severe combined immunodeficiency (SCID), infantile neutrophilic disorder resembling...
10.
Thouenon R, Chentout L, Moreno-Corona N, Poggi L, Lombardi E, Hoareau B, et al.
J Exp Med
. 2023 Mar;
220(6).
PMID: 36917008
Here, we report on a heterozygous interferon regulatory factor 4 (IRF4) missense variant identified in three patients from a multigeneration family with hypogammaglobulinemia. Patients' low blood plasmablast/plasma cell and naïve...