Marita L Rodriguez
Overview
Explore the profile of Marita L Rodriguez including associated specialties, affiliations and a list of published articles.
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13
Citations
719
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Recent Articles
1.
Rodriguez M, Beussman K, Chun K, Walzer M, Yang X, Murry C, et al.
ACS Biomater Sci Eng
. 2021 Jan;
5(8):3876-3888.
PMID: 33438427
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) can be utilized to understand the mechanisms underlying the development and progression of heart disease, as well as to develop better interventions and treatments...
2.
Becker B, Rodriguez M, Werner T, Stenzig J, Eschenhagen T, Hirt M
J Vis Exp
. 2020 May;
(159).
PMID: 32449726
Afterload is known to drive the development of both physiological and pathological cardiac states. As such, studying the outcomes of altered afterload states could yield important insights into the mechanisms...
3.
Rodriguez M, Werner T, Becker B, Eschenhagen T, Hirt M
ACS Biomater Sci Eng
. 2019 Oct;
5(7):3663-3675.
PMID: 31637285
Afterload plays important roles during heart development and disease progression, however, studying these effects in a laboratory setting is challenging. Current techniques lack the ability to precisely and reversibly alter...
4.
Yang X, Rodriguez M, Leonard A, Sun L, Fischer K, Wang Y, et al.
Stem Cell Reports
. 2019 Oct;
13(4):657-668.
PMID: 31564645
Although human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have emerged as a novel platform for heart regeneration, disease modeling, and drug screening, their immaturity significantly hinders their application. A hallmark of...
5.
Author Correction: Differentiation of cardiomyocytes and generation of human engineered heart tissue
Breckwoldt K, Breniere-Letuffe D, Mannhardt I, Schulze T, Ulmer B, Werner T, et al.
Nat Protoc
. 2019 Aug;
14(9):2748.
PMID: 31384055
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Breckwoldt K, Letuffe-Breniere D, Mannhardt I, Schulze T, Ulmer B, Werner T, et al.
Nat Protoc
. 2017 May;
12(6):1177-1197.
PMID: 28492526
Since the advent of the generation of human induced pluripotent stem cells (hiPSCs), numerous protocols have been developed to differentiate hiPSCs into cardiomyocytes and then subsequently assess their ability to...
7.
Han S, Rodriguez M, Al-Rekabi Z, Sniadecki N
Cell Adh Migr
. 2016 Sep;
10(5):529-539.
PMID: 27588610
Migration of a fibroblast along a collagen fiber can be regarded as cell locomotion in one-dimension (1D). In this process, a cell protrudes forward, forms a new adhesion, produces traction...
8.
Beussman K, Rodriguez M, Leonard A, Taparia N, Thompson C, Sniadecki N
Methods
. 2015 Sep;
94:43-50.
PMID: 26344757
Stem cell-derived cardiomyocytes have the potential to be used to study heart disease and maturation, screen drug treatments, and restore heart function. Here, we discuss the procedures involved in using...
9.
Kuppusamy K, Jones D, Sperber H, Madan A, Fischer K, Rodriguez M, et al.
Proc Natl Acad Sci U S A
. 2015 May;
112(21):E2785-94.
PMID: 25964336
In metazoans, transition from fetal to adult heart is accompanied by a switch in energy metabolism-glycolysis to fatty acid oxidation. The molecular factors regulating this metabolic switch remain largely unexplored....
10.
Rodriguez M, Graham B, Pabon L, Han S, Murry C, Sniadecki N
J Biomech Eng
. 2014 Mar;
136(5):051005.
PMID: 24615475
Human stem cell-derived cardiomyocytes hold promise for heart repair, disease modeling, drug screening, and for studies of developmental biology. All of these applications can be improved by assessing the contractility...