Marissa Suarez
Overview
Explore the profile of Marissa Suarez including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
242
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0
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Recent Articles
1.
Ramirez P, Vollbrecht T, Acosta F, Suarez M, Angerstein A, Wallace J, et al.
Virology
. 2022 Dec;
578:154-162.
PMID: 36577173
A primary function of HIV-1 Nef is the enhancement of viral infectivity and replication. Whether counteraction of the antiretroviral proteins SERINC3 and SERINC5 is the cause of this positive influence...
2.
Kwon Y, Kaake R, Echeverria I, Suarez M, Karimian Shamsabadi M, Stoneham C, et al.
Nat Struct Mol Biol
. 2020 Jul;
27(9):822-828.
PMID: 32719457
The HIV-1 Nef protein suppresses multiple immune surveillance mechanisms to promote viral pathogenesis and is an attractive target for the development of novel therapeutics. A key function of Nef is...
3.
Stoneham C, Ramirez P, Singh R, Suarez M, Debray A, Lim C, et al.
J Virol
. 2020 Jan;
94(7).
PMID: 31941773
The cellular protein SERINC5 inhibits the infectivity of diverse retroviruses, and its activity is counteracted by the glycosylated Gag (glycoGag) protein of murine leukemia virus (MLV), the S2 protein of...
4.
Jia X, Weber E, Tokarev A, Lewinski M, Rizk M, Suarez M, et al.
Elife
. 2014 May;
3:e02362.
PMID: 24843023
BST2/tetherin, an antiviral restriction factor, inhibits the release of enveloped viruses from the cell surface. Human immunodeficiency virus-1 (HIV-1) antagonizes BST2 through viral protein u (Vpu), which downregulates BST2 from...
5.
Tokarev A, Suarez M, Kwan W, Fitzpatrick K, Singh R, Guatelli J
J Virol
. 2012 Dec;
87(4):2046-57.
PMID: 23221546
BST2 (HM1.24; CD317; tetherin) is an interferon-inducible transmembrane protein that restricts the release of several enveloped viruses, including HIV, from infected cells. Before its activity as an antiviral factor was...
6.
Semple G, Santora V, Smith J, Covel J, Hayashi R, Gallardo C, et al.
Bioorg Med Chem Lett
. 2011 Dec;
22(1):71-5.
PMID: 22172695
The design of a new clinical candidate histamine-H(3) receptor antagonist for the potential treatment of excessive daytime sleepiness (EDS) is described. Phenethyl-R-2-methylpyrrolidine containing biphenylsulfonamide compounds were modified by replacement of...
7.
Covel J, Santora V, Smith J, Hayashi R, Gallardo C, Weinhouse M, et al.
J Med Chem
. 2009 Sep;
52(18):5603-11.
PMID: 19722526
Antagonism of the histamine-H(3) receptor is one tactic being explored to increase wakefulness for the treatment of disorders such as excessive daytime sleepiness (EDS) as well as other sleep or...
8.
Santora V, Covel J, Hayashi R, Hofilena B, Ibarra J, Pulley M, et al.
Bioorg Med Chem Lett
. 2008 Jun;
18(14):4133-6.
PMID: 18554904
A new series of H(3) antagonists derived from the natural product Conessine are presented. Several compounds from these new series retain the potency and selectivity of earlier diamine based analogs...
9.
Santora V, Covel J, Hayashi R, Hofilena B, Ibarra J, Pulley M, et al.
Bioorg Med Chem Lett
. 2008 Jan;
18(4):1490-4.
PMID: 18194865
A new family of Histamine H(3) receptor antagonists (5a-t) has been prepared based on the structure of the natural product Conessine, a known H(3) antagonist. Several members of the new...