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Marisa Jadna Silva Frederico

Explore the profile of Marisa Jadna Silva Frederico including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 88
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Recent Articles
1.
Frederico M, Sulis P, Pereira L, Rey D, Aragon M, Silva F
Nutrients . 2025 Jan; 17(2). PMID: 39861427
Diabetes mellitus is a metabolic syndrome that has grown globally to become a significant public health challenge. Hypothesizing that the plasma membrane protein, transient receptor potential ankyrin-1, is a pivotal...
2.
Jones Severino Vasconcelos Q, Frederico M, Alves R, Bandeira T, de Moraes M, Aragao G
Future Microbiol . 2023 Nov; 19:213-226. PMID: 37934065
To evaluate the effects of whey protein (WP) supplementation (1.24 mg/g, 24 days) in rats with autism spectrum disorder (ASD) induced by valproic acid (400 mg/kg, single dose). Wistar rats...
3.
Frederico M, Cipriani A, Heim J, Mendes A, Aragon M, Gaspar J, et al.
Pharmaceuticals (Basel) . 2023 Aug; 16(8). PMID: 37631083
This pre-clinical study investigated the transient receptor potential ankyrin-1 (TRPA1) channels on modulating targets for glucose homeostasis using agonists: the electrophilic agonists, cinnamaldehyde (CIN) and allyl isothiocyanate (AITC), and the...
4.
de Jesus Guimaraes C, Carneiro T, Frederico M, de Carvalho G, Little M, Freire V, et al.
Pharmaceutics . 2023 Apr; 15(4). PMID: 37111767
LASSBio-1920 was synthesized due to the poor solubility of its natural precursor, combretastatin A4 (CA4). The cytotoxic potential of the compound against human colorectal cancer cells (HCT-116) and non-small cell...
5.
Sulis P, Mendes A, Fernandes T, Frederico M, Rey D, Aragon M, et al.
Biochimie . 2023 Apr; 212:85-94. PMID: 37080419
A chalcone analogue, (E)-3-(phenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (DMU 101), was synthesized using classic base catalysis and Claisen-Schmidt condensation, and then screened for its antidiabetic properties. The compound's effects on glucose and lipid metabolism...
6.
Pires Mendes C, Postal B, Frederico M, Marques Elias R, Aiceles de Medeiros Pinto V, da Fonte Ramos C, et al.
Bioorg Chem . 2021 Jul; 114:105157. PMID: 34328855
A new library of hybrid compounds that combine the functional parts of glibenclamide and pioglitazone was designed and developed. Compounds were screened for their antihyperglycemic effects on the glucose tolerance...
7.
Gomes Castro A, Cazarolli L, Frederico M, Dambros B, de Carvalho F, Aiceles de Medeiros Pinto V, et al.
Eur J Pharmacol . 2021 Jun; 907:174250. PMID: 34118223
We studied the effect and the mechanisms of action of 2α,3β,23-trihydroxyolean-12-ene (THO), from Croton heterodoxus Baill. (Euphorbiaceae), in glucose uptake in hyperglycemic rats. The effect of in vivo pretreatment with...
8.
Rey D, Fernandes T, Sulis P, Goncalves R, Sepulveda R M, Frederico M, et al.
Chem Biol Interact . 2020 Jul; 330:109198. PMID: 32692981
Quercetin 3-O-beta-d-glucopyranoside (isoquercetin) is one of the most frequent metabolites of the Passiflora ligularis Juss. The purpose of this study was to investigate the effect of the aqueous extract and...
9.
Rey D, Sulis P, Fernandes T, Goncalves R, Frederico M, Costa G, et al.
Cell Calcium . 2019 Apr; 80:56-62. PMID: 30965223
Astragalin is a flavonol glycoside with several biological activities, including antidiabetic properties. The objective of this study was to investigate the effects of astragalin on glycaemia and insulin secretion, in...
10.
Sulis P, Dambros B, Mascarello A, Dos Santos A, Yunes R, Nunes R, et al.
J Cell Physiol . 2018 Nov; 234(7):10138-10147. PMID: 30417369
Aim: To investigate the mechanism of action of sulfonyl(thio)urea derivative (SD) on glycemia and on insulin secretion in pancreatic islets. Methods: Wistar rats were divided into hyperglycemic control group, rats...