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Mario Stefanini

Explore the profile of Mario Stefanini including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 525
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Recent Articles
1.
Di Persio S, Saracino R, Fera S, Muciaccia B, Esposito V, Boitani C, et al.
Development . 2017 Aug; 144(19):3430-3439. PMID: 28827392
The human spermatogonial compartment is essential for daily production of millions of sperm. Despite this crucial role, the molecular signature, kinetic behavior and regulation of human spermatogonia are poorly understood....
2.
Muciaccia B, Boitani C, Berloco B, Nudo F, Spadetta G, Stefanini M, et al.
Biol Reprod . 2013 Aug; 89(3):60. PMID: 23946533
To date, in the human seminiferous epithelium, only six associations of cell types have been distinguished, subdividing the epithelial cycle into six stages of very different duration. This hampers comparisons...
3.
Dovere L, Fera S, Grasso M, Lamberti D, Gargioli C, Muciaccia B, et al.
PLoS One . 2013 Apr; 8(4):e59431. PMID: 23613711
In mammals, the biological activity of the stem/progenitor compartment sustains production of mature gametes through spermatogenesis. Spermatogonial stem cells and their progeny belong to the class of undifferentiated spermatogonia, a...
4.
Muciaccia B, Pensini S, Culasso F, Padula F, Paoli D, Gandini L, et al.
Hum Reprod . 2012 Jun; 27(8):2267-76. PMID: 22647452
Background: Clusterin, a heterodimeric glycoprotein found at several sites in the human male reproductive tract, could be a marker of morphologically abnormal spermatozoa, while TUNEL positivity indicates DNA fragmentation. Metabolic...
5.
Grasso M, Fuso A, Dovere L, de Rooij D, Stefanini M, Boitani C, et al.
Reproduction . 2011 Dec; 143(3):325-32. PMID: 22143971
In mice and other mammals, spermatogenesis is maintained by spermatogonial stem cells (SSCs), a cell population belonging to undifferentiated type A spermatogonia. In the accepted model of SSC self-renewal, Asingle...
6.
Scaldaferri M, Fera S, Grisanti L, Sanchez M, Stefanini M, De Felici M, et al.
Int J Dev Biol . 2011 May; 55(2):209-14. PMID: 21553385
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the “side population” (SP) phenotype have been...
7.
Muciaccia B, Sette C, Paronetto M, Barchi M, Pensini S, DAgostino A, et al.
Hum Reprod . 2010 Jul; 25(9):2188-202. PMID: 20601678
Background: TR-KIT, a truncated form of KIT (the KITL receptor), corresponding to the c-terminal half of the intracellular split tyrosine kinase domain, is expressed during the haploid stages of mouse...
8.
Latini S, Chiarpotto M, Muciaccia B, Vaccari S, Barberi M, Guglielmo M, et al.
Mol Cell Endocrinol . 2010 Feb; 320(1-2):34-44. PMID: 20138961
Pituitary adenylate cyclase activating polypeptide (PACAP) is transiently expressed in preovulatory follicles of different species and positively affects parameters correlated with the ovulatory process. It has also been shown to...
9.
Grisanti L, Falciatori I, Grasso M, Dovere L, Fera S, Muciaccia B, et al.
Stem Cells . 2009 Aug; 27(12):3043-52. PMID: 19711452
Spermatogenesis is maintained by a pool of spermatogonial stem cells (SSCs). Analyses of the molecular profile of SSCs have revealed the existence of subsets, indicating that the stem cell population...
10.
Grisanti L, Corallini S, Fera S, Muciaccia B, Stefanini M, Witke W, et al.
Differentiation . 2009 Jun; 78(2-3):131-6. PMID: 19541401
Spermatogonial stem cells (SSC) ensure continuous production of mammalian male gametes. In rodents, the SSC are Asingle spermatogonia (As). Gene loss and gain-of-function mutations have provided some clues into SSC...