Laura Grisanti
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Explore the profile of Laura Grisanti including associated specialties, affiliations and a list of published articles.
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16
Citations
680
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Recent Articles
1.
Durens M, Baljinnyam E, Grisanti L, Hu R, Marro S
Stem Cell Res
. 2024 Jun;
79:103455.
PMID: 38896969
Calcium indicators are sensitive tools to image neural activity. However, their use in human induced pluripotent stem cells (iPSC)-derived neurons is limited by silencing of the transgene. We generated the...
2.
Martino P, Sunkara R, Heitman N, Rangl M, Brown A, Saxena N, et al.
Nat Cell Biol
. 2023 Jan;
25(2):222-234.
PMID: 36717629
Substantial follicle remodelling during the regression phase of the hair growth cycle is coordinated by the contraction of the dermal sheath smooth muscle, but how dermal-sheath-generated forces are regulated is...
3.
Choi S, Zhang B, Ma S, Gonzalez-Celeiro M, Stein D, Jin X, et al.
Nature
. 2021 Apr;
592(7854):428-432.
PMID: 33790465
Chronic, sustained exposure to stressors can profoundly affect tissue homeostasis, although the mechanisms by which these changes occur are largely unknown. Here we report that the stress hormone corticosterone-which is...
4.
Heitman N, Sennett R, Mok K, Saxena N, Srivastava D, Martino P, et al.
Science
. 2019 Dec;
367(6474):161-166.
PMID: 31857493
Tissue homeostasis requires the balance of growth by cell production and regression through cell loss. In the hair cycle, during follicle regression, the niche traverses the skin through an unknown...
5.
Mok K, Saxena N, Heitman N, Grisanti L, Srivastava D, Muraro M, et al.
Dev Cell
. 2019 Jan;
48(1):32-48.e5.
PMID: 30595537
Cell fate transitions are essential for specification of stem cells and their niches, but the precise timing and sequence of molecular events during embryonic development are largely unknown. Here, we...
6.
Grisanti L, Revenkova E, Gordon R, Iomini C
Development
. 2016 Apr;
143(12):2160-71.
PMID: 27122169
Primary cilia have been linked to signaling pathways involved in cell proliferation, cell motility and cell polarity. Defects in ciliary function result in developmental abnormalities and multiple ciliopathies. Patients affected...
7.
Sennett R, Wang Z, Rezza A, Grisanti L, Roitershtein N, Sicchio C, et al.
Dev Cell
. 2015 Aug;
34(5):577-91.
PMID: 26256211
Defining the unique molecular features of progenitors and their niche requires a genome-wide, whole-tissue approach with cellular resolution. Here, we co-isolate embryonic hair follicle (HF) placode and dermal condensate cells,...
8.
Tsai S, Sennett R, Rezza A, Clavel C, Grisanti L, Zemla R, et al.
Dev Biol
. 2013 Dec;
385(2):179-88.
PMID: 24309208
Broad dermal Wnt signaling is required for patterned induction of hair follicle placodes and subsequent Wnt signaling in placode stem cells is essential for induction of dermal condensates, cell clusters...
9.
Grisanti L, Rezza A, Clavel C, Sennett R, Rendl M
J Invest Dermatol
. 2013 May;
133(10):2332-2339.
PMID: 23677168
Systematic ablation of previously identified dermal papilla (DP) signature genes in embryonic DP precursors will reveal their functional roles during hair follicle morphogenesis. In this study, we validate Enpp2/Autotaxin as...
10.
Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, et al.
Dev Cell
. 2012 Nov;
23(5):981-94.
PMID: 23153495
How dermal papilla (DP) niche cells regulate hair follicle progenitors to control hair growth remains unclear. Using Tbx18(Cre) to target embryonic DP precursors, we ablate the transcription factor Sox2 early...