Mario Pavani
Overview
Explore the profile of Mario Pavani including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
197
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Jara J, Rojas D, Castro-Castillo V, Fuentes-Retamal S, Sandoval-Acuna C, Parra E, et al.
Toxicol In Vitro
. 2020 Mar;
65:104814.
PMID: 32112803
Introduction: Colorectal cancer (CRC) is a critical health issue worldwide. The high rate of liver and lung metastasis associated with CRC creates a significant barrier to effective and efficient therapy....
2.
Fuentes-Retamal S, Sandoval-Acuna C, Peredo-Silva L, Guzman-Rivera D, Pavani M, Torrealba N, et al.
Cells
. 2020 Feb;
9(2).
PMID: 32053908
The mitochondrion has emerged as a promising therapeutic target for novel cancer treatments because of its essential role in tumorigenesis and resistance to chemotherapy. Previously, we described a natural compound,...
3.
Urra F, Munoz F, Cordova-Delgado M, Ramirez M, Pena-Ahumada B, Rios M, et al.
Sci Rep
. 2018 Sep;
8(1):13190.
PMID: 30181620
Highly malignant triple-negative breast cancer (TNBC) cells rely mostly on glycolysis to maintain cellular homeostasis; however, mitochondria are still required for migration and metastasis. Taking advantage of the metabolic flexibility...
4.
Peredo-Silva L, Fuentes-Retamal S, Sandoval-Acuna C, Pavani M, Maya J, Castro-Castillo V, et al.
Toxicol Appl Pharmacol
. 2017 Jun;
329:334-346.
PMID: 28647477
We previously demonstrated that alkyl gallates coupled to triphenylphosphine have a selective and efficient antiproliferative effect by inducing mitochondrial uncoupling in vitro due to the increased mitochondrial transmembrane potential of...
5.
Sandoval-Acuna C, Fuentes-Retamal S, Guzman-Rivera D, Peredo-Silva L, Madrid-Rojas M, Rebolledo S, et al.
Toxicol Appl Pharmacol
. 2016 Aug;
309:2-14.
PMID: 27554043
Mitochondrion is an accepted molecular target in cancer treatment since it exhibits a higher transmembrane potential in cancer cells, making it susceptible to be targeted by lipophilic-delocalized cations of triphenylphosphonium...
6.
Urra F, Cordova-Delgado M, Lapier M, Orellana-Manzano A, Acevedo-Arevalo L, Pessoa-Mahana H, et al.
Toxicol Appl Pharmacol
. 2015 Dec;
291:46-57.
PMID: 26712467
Mitochondria participate in several distinctiveness of cancer cell, being a promising target for the design of anti-cancer compounds. Previously, we described that ortho-carbonyl hydroquinone scaffold 14 inhibits the complex I-dependent...
7.
Jana F, Faini F, Lapier M, Pavani M, Kemmerling U, Morello A, et al.
Toxicol Appl Pharmacol
. 2013 Jun;
272(2):356-64.
PMID: 23777606
Changes in mitochondrial ATP synthesis can affect the function of tumor cells due to the dependence of the first step of glycolysis on mitochondrial ATP. The oxidative phosphorylation (OXPHOS) system...
8.
Urra F, Martinez-Cifuentes M, Pavani M, Lapier M, Jana-Prado F, Parra E, et al.
Toxicol Appl Pharmacol
. 2013 Jan;
267(3):218-27.
PMID: 23333614
Tumor cells present a known metabolic reprogramming, which makes them more susceptible for a selective cellular death by modifying its mitochondrial bioenergetics. Anticancer action of the antioxidant 9,10-dihydroxy-4,4-dimethyl-5,8-dihydroanthracen-1(4H)-one (HQ) on...
9.
Plaza C, Pavani M, Araya-Maturana R, Pezoa J, Maya J, Morello A, et al.
In Vivo
. 2009 Dec;
23(6):959-67.
PMID: 20023240
Background: Multidrug resistance (MDR) continues being the major obstacle for successful anticancer chemotherapy. Materials And Methods: The action of nordihydroguaiaretic acid (NDGA) and its tetra-acetylated derivative (NDGATA) on TA3 mouse...
10.
Plaza C, Pavani M, Faundez M, Maya J, Morello A, Becker M, et al.
In Vivo
. 2008 Jul;
22(3):353-61.
PMID: 18610748
The effects of nordihydroguaiaretic acid (NDGA) and its tetraacetylated derivative (NDGATA) on the growth, oxygen consumption, adenosine 5'-triphosphate (ATP) level and viability of mouse mammary adenocarcinoma TA3 and its multiresistant...