Mario P Colombo
Overview
Explore the profile of Mario P Colombo including associated specialties, affiliations and a list of published articles.
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Articles
143
Citations
8560
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Recent Articles
11.
Cordero-Sanchez C, Pessolano E, Riva B, Vismara M, Trivigno S, Clemente N, et al.
Blood Adv
. 2022 Jun;
6(15):4471-4484.
PMID: 35696753
Store-operated Ca2+-entry is a cellular mechanism that governs the replenishment of intracellular stores of Ca2+ upon depletion caused by the opening of intracellular Ca2+-channels. Gain-of-function mutations of the 2 key...
12.
Tripodo C, Bassani B, Jachetti E, Cancila V, Chiodoni C, Portararo P, et al.
Elife
. 2022 Apr;
11.
PMID: 35471185
Neutrophil extracellular traps (NETs) are web-like chromatin structures composed by dsDNA and histones, decorated with antimicrobial proteins. Their interaction with dendritic cells (DCs) allows DC activation and maturation toward presentation...
13.
Bellone M, Bregni M, Bronte V, Ugel S, Ferrucci P, Di Nicola M, et al.
Cancer Immunol Immunother
. 2021 Nov;
71(7):1777-1786.
PMID: 34755203
No abstract available.
14.
Enriquez C, Cancila V, Ferri R, Sulsenti R, Fischetti I, Milani M, et al.
Cancer Res
. 2021 Jun;
81(16):4257-4274.
PMID: 34185677
Fatal neuroendocrine differentiation (NED) of castration-resistant prostate cancer is a recurrent mechanism of resistance to androgen deprivation therapies (ADT) and antiandrogen receptor pathway inhibitors (ARPI) in patients. The design of...
15.
Sangaletti S, Botti L, Gulino A, Lecis D, Bassani B, Portararo P, et al.
iScience
. 2021 Jun;
24(6):102510.
PMID: 34142027
The secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein with unexpected immunosuppressive function in myeloid cells. We investigated the role of SPARC in autoimmunity using the...
16.
Bassani B, Tripodo C, Portararo P, Gulino A, Botti L, Chiodoni C, et al.
Front Immunol
. 2021 Jun;
12:662048.
PMID: 34084166
Background: Within the bone marrow (BM), mature T cells are maintained under homeostatic conditions to facilitate proper hematopoietic development. This homeostasis depends upon a peculiar elevated frequency of regulatory T...
17.
Morello G, Cancila V, La Rosa M, Germano G, Lecis D, Amodio V, et al.
Cancer Immunol Res
. 2021 May;
9(7):825-837.
PMID: 33941587
Tumors undergo dynamic immunoediting as part of a process that balances immunologic sensing of emerging neoantigens and evasion from immune responses. Tumor-infiltrating lymphocytes (TIL) comprise heterogeneous subsets of peripheral T...
18.
Mather R, Parolia A, Carson S, Venalainen E, Roig-Carles D, Jaber M, et al.
Mol Oncol
. 2021 Apr;
15(7):1921-1941.
PMID: 33793068
Metastatic neuroendocrine prostate cancer (NEPC) is a highly aggressive disease, whose incidence is rising. Long noncoding RNAs (lncRNAs) represent a large family of disease- and tissue-specific transcripts, most of which...
19.
Sulsenti R, Frossi B, Bongiovanni L, Cancila V, Ostano P, Fischetti I, et al.
Front Immunol
. 2021 Mar;
12:622001.
PMID: 33737929
A relevant fraction of castration-resistant prostate cancers (CRPC) evolve into fatal neuroendocrine (NEPC) tumors in resistance to androgen deprivation and/or inhibitors of androgen receptor pathway. Therefore, effective drugs against both...
20.
Jachetti E, Sangaletti S, Chiodoni C, Ferrara R, Colombo M
Cell Immunol
. 2021 Feb;
362:104301.
PMID: 33588246
Immuno checkpoint blockade (ICB) targeting the PD-1/PD-L1 axis is the main breakthrough for the treatment of several cancers. Nevertheless, not all patients benefit from this treatment and clinical response not...