Marinella G Callow
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Explore the profile of Marinella G Callow including associated specialties, affiliations and a list of published articles.
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6
Citations
378
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Recent Articles
1.
Feng S, Callow M, Fortin J, Khan Z, Bray D, Costa M, et al.
Proc Natl Acad Sci U S A
. 2022 Apr;
119(18):e2120512119.
PMID: 35471904
Mutant-specific inhibitors of KRASG12C, such as AMG510 (sotorasib) and MRTX849 (adagrasib), offer the unprecedented opportunity to inhibit KRAS, the most frequently mutated and heretofore undruggable oncoprotein. While clinical data are...
2.
Callow M, Watanabe C, Wickliffe K, Bainer R, Kummerfield S, Weng J, et al.
Cell Death Dis
. 2018 Feb;
9(3):261.
PMID: 29449584
The necroptotic cell death pathway is a key component of human pathogen defense that can become aberrantly derepressed during tissue homeostasis to contribute to multiple types of tissue damage and...
3.
Callow M, Tran H, Phu L, Lau T, Lee J, Sandoval W, et al.
PLoS One
. 2011 Jul;
6(7):e22595.
PMID: 21799911
Canonical Wnt signaling is controlled intracellularly by the level of β-catenin protein, which is dependent on Axin scaffolding of a complex that phosphorylates β-catenin to target it for ubiquitylation and...
4.
Callow M, Zozulya S, Gishizky M, Jallal B, Smeal T
J Cell Sci
. 2005 Apr;
118(Pt 9):1861-72.
PMID: 15827085
Precise spatial and temporal regulation of Rho GTPases is required in controlling F-actin-based changes in cell morphology. The molecular mechanisms through which microtubules (MTs) modulate the activity of RhoGTPases and...
5.
Gross E, Callow M, Waldbaum L, Thomas S, Ruggieri R
J Biol Chem
. 2002 Feb;
277(16):13873-82.
PMID: 11836244
Mitogen-activated protein (MAP) kinase pathways are three-kinase modules that mediate diverse cellular processes and have been highly conserved among eukaryotes. By using a functional complementation screen in yeast, we have...
6.
Callow M, Clairvoyant F, Zhu S, Schryver B, Whyte D, Bischoff J, et al.
J Biol Chem
. 2001 Oct;
277(1):550-8.
PMID: 11668177
p21-activated protein kinase (PAK) serine/threonine kinases are important effectors of Rho family GTPases and have been implicated in the regulation of cell morphology and motility, as well as in cell...