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Marina McDew-White

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Articles 31
Citations 789
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Recent Articles
1.
Premadasa L, McDew-White M, Romero L, Gondo B, Drawec J, Ling B, et al.
bioRxiv . 2024 Nov; PMID: 39605466
The epigenetic mechanisms driving persistent gastrointestinal mucosal dysfunction in HIV/SIV infection is an understudied topic. Using reduced-representation bisulfite sequencing, we identified HIV/SIV infection in combination anti-retroviral therapy (cART)-naive rhesus macaques...
2.
Amambua-Ngwa A, Button-Simons K, Li X, Kumar S, Brenneman K, Ferrari M, et al.
Nat Microbiol . 2023 May; 8(7):1213-1226. PMID: 37169919
Malaria parasites break down host haemoglobin into peptides and amino acids in the digestive vacuole for export to the parasite cytoplasm for growth: interrupting this process is central to the...
3.
Premadasa L, Lee E, McDew-White M, Alvarez X, Jayakumar S, Ling B, et al.
JCI Insight . 2023 Apr; 8(7). PMID: 37036007
Intestinal epithelial barrier dysfunction, a hallmark of HIV/SIV infection, persists despite viral suppression by combination antiretroviral therapy (cART). Emerging evidence suggests a critical role for long noncoding RNAs (lncRNAs) in...
4.
Kopcho S, McDew-White M, Naushad W, Mohan M, Okeoma C
Viruses . 2023 Mar; 15(3). PMID: 36992332
In this follow-up study, we investigated the abundance and compartmentalization of blood plasma extracellular miRNA (exmiRNA) into lipid-based carriers-blood plasma extracellular vesicles (EVs) and non-lipid-based carriers-extracellular condensates (ECs) during SIV...
5.
Kopcho S, McDew-White M, Naushad W, Mohan M, Okeoma C
Viruses . 2023 Mar; 15(3). PMID: 36992331
: This is Manuscript 1 of a two-part Manuscript of the same series. Here, we present findings from our first set of studies on the abundance and compartmentalization of blood...
6.
McDew-White M, Lee E, Premadasa L, Alvarez X, Okeoma C, Mohan M
J Neuroinflammation . 2023 Mar; 20(1):62. PMID: 36890518
Background: Although the advent of combination anti-retroviral therapy (cART) has transformed HIV into a manageable chronic disease, an estimated 30-50% of people living with HIV (PLWH) exhibit cognitive and motor...
7.
Ebel E, Kim B, McDew-White M, Egan E, Anderson T, Petrov D
bioRxiv . 2023 Feb; PMID: 36778235
Sequence variation among antigenic genes enables malaria parasites to evade host immunity. Using long sequence reads from haploid clones from a mutation accumulation experiment, we detect diversity inconsistent with simple...
8.
Kaddour H, McDew-White M, Madeira M, Tranquille M, Tsirka S, Mohan M, et al.
J Neuroinflammation . 2022 Sep; 19(1):225. PMID: 36096938
Background: Early invasion of the central nervous system (CNS) by human immunodeficiency virus (HIV) (Gray et al. in Brain Pathol 6:1-15, 1996; An et al. in Ann Neurol 40:611-6172, 1996),...
9.
Kumar S, Li X, McDew-White M, Reyes A, Delgado E, Sayeed A, et al.
Front Cell Infect Microbiol . 2022 Jun; 12:878496. PMID: 35711667
What genes determine growth and nutrient utilization in asexual blood-stage malaria parasites? Competition experiments between NF54, clone 3D7, a lab-adapted African parasite, and a recently isolated Asian parasite (NHP4026) reveal...
10.
Nair S, Li X, Arya G, McDew-White M, Ferrari M, Anderson T
Antimicrob Agents Chemother . 2022 Apr; 66(5):e0152921. PMID: 35465723
Drug resistance mutations tend to disrupt key physiological processes and frequently carry fitness costs, which are a central determinant of the rate of spread of these mutations in natural populations....