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Marilia Barros

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Recent Articles
11.
Hur J, Frost G, Wu X, Crump C, Pan S, Wong E, et al.
Nature . 2020 Sep; 586(7831):735-740. PMID: 32879487
Innate immunity is associated with Alzheimer's disease, but the influence of immune activation on the production of amyloid-β is unknown. Here we identify interferon-induced transmembrane protein 3 (IFITM3) as a...
12.
Pereira L, Maior R, Barros M
Front Behav Neurosci . 2020 Aug; 14:123. PMID: 32765232
Temporal information about food availability can be easily entrained, as in the case of fixed feeding routines of captive animals. A sudden unintentional or deliberate delay (e.g., food deprivation-FD) leads...
13.
Frankowska M, Jesus F, Muhle C, Pacheco J, Maior R, Sadakierska-Chudy A, et al.
Addict Biol . 2020 Aug; 26(3):e12955. PMID: 32761719
Cocaine addiction is a severe psychiatric condition for which currently no effective pharmacotherapy is available. Brain mechanisms for the establishment of addiction-related behaviors are still not fully understood, and specific...
14.
Easton A, Barros M, Lever C
Curr Top Behav Neurosci . 2020 May; 45:29-45. PMID: 32462614
Whilst acetylcholine has long been linked to memory, there have been significant questions about its specific role. In particular, the effects of cholinergic manipulations in primates and rodents has often...
15.
Barros M, Houlihan W, Paresi C, Brendel M, Rynearson K, Lee C, et al.
Langmuir . 2020 May; 36(23):6569-6579. PMID: 32432881
γ-Secretase is a multisubunit complex that catalyzes intramembranous cleavage of transmembrane proteins. The lipid environment forms membrane microdomains that serve as spatio-temporal platforms for proteins to function properly. Despite substantial...
16.
Zhao J, Xiao Y, Liu X, Kim S, Wu X, Barros M, et al.
Chem Commun (Camb) . 2020 Feb; 56(17):2578-2581. PMID: 32016207
Combining NMR, mass spectrometry, AlphaLISA and cell assays, we discovered a compound C1 that binds C-terminal juxtamembrane lysines at the transmembrane domain of the amyloid precursor protein (APPTM) and inhibits...
17.
Vannuchi C, Costa C, de Jesus F, Maior R, Barros M
Behav Brain Res . 2019 Nov; 379:112334. PMID: 31697981
In the spontaneous object-location (SOL) task, the ability to recognize where stimuli were located in a past encounter is assessed. Even if widely used in rodents, several aspects can affect...
18.
Pereira L, Maior R, Barros M
Front Neurosci . 2019 Sep; 13:913. PMID: 31543757
Restraint is widely used to experimentally assess stress-induced effects. Surprisingly, little is known on how marmosets - an increasingly used small primate - process and respond to restraint stress. Here,...
19.
Gonczarowska N, Tomaz C, Caixeta F, Malcher-Lopes R, Barros M, Nishijo H, et al.
Psychopharmacology (Berl) . 2019 Jun; 236(12):3413-3419. PMID: 31250073
Rationale: The endocannabinoid system (eCS) is an important modulator of social anxiety and social reward, as well as memory functions. Objectives: The present study evaluated the role of eCS in...
20.
Pereira L, Duarte R, Maior R, Barros M
Physiol Behav . 2018 Aug; 195:112-117. PMID: 30063904
The behavior, cortisol concentration and cerebral hemisphere activity of twelve marmoset monkeys were determined during standardized predatory stress-related events. Each subject was submitted to three 5-min trials, randomly held at...