Marielle J van Breemen
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Explore the profile of Marielle J van Breemen including associated specialties, affiliations and a list of published articles.
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25
Citations
2145
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Recent Articles
1.
Grobben M, Bakker M, Schriek A, Levels L, Umotoy J, Tejjani K, et al.
PLoS Pathog
. 2024 Dec;
20(12):e1012739.
PMID: 39661636
HIV-1 infection leads to chronic disease requiring life-long treatment and therefore alternative therapeutics, a cure and/or a protective vaccine are needed. Antibody-mediated effector functions could have a role in the...
2.
Brinkkemper M, Kerster G, Brouwer P, Tran A, Torres J, Ettema R, et al.
PLoS Pathog
. 2024 Oct;
20(10):e1012558.
PMID: 39361585
An effective human immunodeficiency virus 1 (HIV-1) vaccine will most likely have to elicit broadly neutralizing antibodies (bNAbs) to overcome the sequence diversity of the envelope glycoprotein (Env). So far,...
3.
Caniels T, Medina-Ramirez M, Zhang J, Sarkar A, Kumar S, LaBranche A, et al.
Cell Rep Med
. 2023 Apr;
4(4):101003.
PMID: 37044090
Targeting germline (gl-) precursors of broadly neutralizing antibodies (bNAbs) is acknowledged as an important strategy for HIV-1 vaccines. The VRC01-class of bNAbs is attractive because of its distinct genetic signature....
4.
Maisonnasse P, Aldon Y, Marc A, Marlin R, Dereuddre-Bosquet N, Kuzmina N, et al.
Nat Commun
. 2021 Oct;
12(1):6097.
PMID: 34671037
Effective treatments against Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) are urgently needed. Monoclonal antibodies have shown promising results in patients. Here, we evaluate the in vivo prophylactic and therapeutic...
5.
Brouwer P, Brinkkemper M, Maisonnasse P, Dereuddre-Bosquet N, Grobben M, Claireaux M, et al.
Cell
. 2021 Feb;
184(5):1188-1200.e19.
PMID: 33577765
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is continuing to disrupt personal lives, global healthcare systems, and economies. Hence, there is an urgent need for a vaccine that...
6.
Brouwer P, Caniels T, van der Straten K, Snitselaar J, Aldon Y, Bangaru S, et al.
Science
. 2020 Jun;
369(6504):643-650.
PMID: 32540902
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a large impact on global health, travel, and economy. Therefore, preventative and therapeutic measures are urgently needed....
7.
Sliepen K, Han B, Bontjer I, Mooij P, Garces F, Behrens A, et al.
Nat Commun
. 2019 May;
10(1):2355.
PMID: 31142746
Stabilized HIV-1 envelope glycoproteins (Env) that resemble the native Env are utilized in vaccination strategies aimed at inducing broadly neutralizing antibodies (bNAbs). To limit the exposure of rare isolate-specific antigenic...
8.
van de Bovenkamp F, Derksen N, van Breemen M, de Taeye S, Ooijevaar-De Heer P, Sanders R, et al.
Front Immunol
. 2018 May;
9:740.
PMID: 29706962
Immunoglobulin G (IgG) can contain -linked glycans in the variable domains, the so-called Fab glycans, in addition to the Fc glycans in the C2 domains. These Fab glycans are acquired...
9.
Medina-Ramirez M, Garces F, Escolano A, Skog P, de Taeye S, Moral-Sanchez I, et al.
J Exp Med
. 2017 Aug;
214(9):2573-2590.
PMID: 28847869
Induction of broadly neutralizing antibodies (bNAbs) by HIV-1 envelope glycoprotein immunogens would be a major advance toward an effective vaccine. A critical step in this process is the activation of...
10.
A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors
de Vries R, Tzarum N, Peng W, Thompson A, Ambepitiya Wickramasinghe I, de la Pena A, et al.
EMBO Mol Med
. 2017 Jul;
9(9):1314-1325.
PMID: 28694323
In June 2013, the first case of human infection with an avian H6N1 virus was reported in a Taiwanese woman. Although this was a single non-fatal case, the virus continues...