Mariantonietta DAmbrosio
Overview
Explore the profile of Mariantonietta DAmbrosio including associated specialties, affiliations and a list of published articles.
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11
Citations
219
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Recent Articles
1.
Reen V, DAmbrosio M, Sogaard P, Tyson K, Leeke B, Clement I, et al.
Sci Adv
. 2025 Jan;
11(3):eadn2811.
PMID: 39813356
Induction of senescence by chemotherapeutic agents arrests cancer cells and activates immune surveillance responses to contribute to therapy outcomes. In this investigation, we searched for ways to enhance the NK-mediated...
2.
Cali B, Troiani M, Bressan S, Attanasio G, Merler S, Moscarda V, et al.
Cancer Cell
. 2024 Sep;
42(10):1676-1692.e11.
PMID: 39303726
Although hypercoagulability is commonly associated with malignancies, whether coagulation factors directly affect tumor cell proliferation remains unclear. Herein, by performing single-cell RNA sequencing (scRNA-seq) of the prostate tumor microenvironment (TME)...
3.
Colucci M, Zumerle S, Bressan S, Gianfanti F, Troiani M, Valdata A, et al.
Cancer Cell
. 2024 Mar;
42(4):646-661.e9.
PMID: 38428412
Cellular senescence can exert dual effects in tumors, either suppressing or promoting tumor progression. The senescence-associated secretory phenotype (SASP), released by senescent cells, plays a crucial role in this dichotomy....
4.
Guccini I, Tang G, To T, Di Rito L, Le Blanc S, Strobel O, et al.
iScience
. 2023 Aug;
26(8):107368.
PMID: 37559908
Although dietary fructose is associated with an elevated risk for pancreatic cancer, the underlying mechanisms remain elusive. Here, we report that ketohexokinase (KHK), the rate-limiting enzyme of fructose metabolism, is...
5.
Troiani M, Colucci M, DAmbrosio M, Guccini I, Pasquini E, Varesi A, et al.
Nat Commun
. 2023 Jul;
14(1):4386.
PMID: 37474528
No abstract available.
6.
Brina D, Ponzoni A, Troiani M, Cali B, Pasquini E, Attanasio G, et al.
Nat Cancer
. 2023 Jul;
4(8):1102-1121.
PMID: 37460872
Cancer is highly infiltrated by myeloid-derived suppressor cells (MDSCs). Currently available immunotherapies do not completely eradicate MDSCs. Through a genome-wide analysis of the translatome of prostate cancers driven by different...
7.
DAmbrosio M, Gil J
Dev Cell
. 2023 Jun;
58(12):1007-1021.
PMID: 37339603
Cellular senescence is a stress response associated with aging and disease, including cancer. Senescent cells undergo a stable cell cycle arrest, undergo a change in morphology and metabolic reprogramming, and...
8.
Bancaro N, Cali B, Troiani M, Elia A, Arzola R, Attanasio G, et al.
Cancer Cell
. 2023 Mar;
41(3):602-619.e11.
PMID: 36868226
Tumor cells promote the recruitment of immunosuppressive neutrophils, a subset of myeloid cells driving immune suppression, tumor proliferation, and treatment resistance. Physiologically, neutrophils are known to have a short half-life....
9.
Troiani M, Colucci M, DAmbrosio M, Guccini I, Pasquini E, Varesi A, et al.
Nat Commun
. 2022 Apr;
13(1):2177.
PMID: 35449130
Cells subjected to treatment with anti-cancer therapies can evade apoptosis through cellular senescence. Persistent senescent tumor cells remain metabolically active, possess a secretory phenotype, and can promote tumor proliferation and...
10.
Gil V, Miranda S, Riisnaes R, Gurel B, DAmbrosio M, Vasciaveo A, et al.
Cancer Res
. 2021 Nov;
81(24):6207-6218.
PMID: 34753775
It has been recognized for decades that ERBB signaling is important in prostate cancer, but targeting ERBB receptors as a therapeutic strategy for prostate cancer has been ineffective clinically. However,...