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Mariana Varela

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Articles 27
Citations 789
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Recent Articles
1.
Selzer Soria E, Gonzalez Campana A, Siaba Serrate A, Varela M, Lagues C, Fauda M, et al.
Arch Argent Pediatr . 2024 Jul; 123(1):e202310222. PMID: 39058378
Primary liver tumors are an increasing indication for pediatric liver transplantation. Here we report the cases of 10 patients who underwent liver transplantation for primary liver tumors in our hospital,...
2.
Pinto R, Bakshi S, Lytras S, Zakaria M, Swingler S, Worrell J, et al.
Nature . 2023 Jun; 619(7969):338-347. PMID: 37380775
Spillover events of avian influenza A viruses (IAVs) to humans could represent the first step in a future pandemic. Several factors that limit the transmission and replication of avian IAVs...
3.
Hardy A, Bakshi S, Furnon W, MacLean O, Gu Q, Varjak M, et al.
mBio . 2023 Apr; 14(3):e0010123. PMID: 37097030
Infected hosts possess two alternative strategies to protect themselves against the negative impact of virus infections: resistance, used to abrogate virus replication, and disease tolerance, used to avoid tissue damage...
4.
Rihn S, Aziz M, Stewart D, Hughes J, Turnbull M, Varela M, et al.
J Virol . 2019 Aug; 93(20). PMID: 31375575
Vesicular stomatitis Indiana virus (VSIV), formerly known as vesicular stomatitis virus (VSV) Indiana (VSV), is a model virus that is exceptionally sensitive to the inhibitory action of interferons (IFNs). Interferons...
5.
Shaw A, Hughes J, Gu Q, Behdenna A, Singer J, Dennis T, et al.
PLoS Biol . 2017 Dec; 15(12):e2004086. PMID: 29253856
The host innate immune response mediated by type I interferon (IFN) and the resulting up-regulation of hundreds of interferon-stimulated genes (ISGs) provide an immediate barrier to virus infection. Studies of...
6.
Varela M, Piras I, Mullan C, Shi X, Tilston-Lunel N, Pinto R, et al.
Virology . 2017 Jun; 509:121-130. PMID: 28628828
Orthobunyaviruses include several recently emerging viruses of significant medical and veterinary importance. There is currently very limited understanding on what determines the host species range of these pathogens. In this...
7.
Gouzil J, Fablet A, Lara E, Caignard G, Cochet M, Kundlacz C, et al.
J Virol . 2016 Nov; 91(1). PMID: 27795408
Importance: Schmallenberg virus (SBV) is an emerging arbovirus of ruminants that spread in Europe between 2011 and 2013. SBV induces fetal abnormalities during gestation, with the central nervous system being...
8.
Ratinier M, Shaw A, Barry G, Gu Q, Di Gialleonardo L, Janowicz A, et al.
J Virol . 2016 Mar; 90(11):5427-39. PMID: 27009961
Unlabelled: Bluetongue virus (BTV) is the causative agent of bluetongue, a major infectious disease of ruminants with serious consequences to both animal health and the economy. The clinical outcome of...
9.
Varela M, Pinto R, Caporale M, Piras I, Taggart A, Seehusen F, et al.
J Virol . 2016 Mar; 90(11):5440-5450. PMID: 26984728
Unlabelled: Serial passage of viruses in cell culture has been traditionally used to attenuate virulence and identify determinants of viral pathogenesis. In a previous study, we found that a strain...
10.
Souza W, Acrani G, Romeiro M, Reis Jr O, Tolardo A, da Silva S, et al.
Infect Genet Evol . 2016 Feb; 40:47-53. PMID: 26921797
Capim and Enseada viruses are members of the genus Orthobunyavirus isolated from mosquitoes and mammals in Brazil. Despite seroprevalence studies indicating human infections in Latin America, these viruses remain relatively...